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TranscriptomicsExamining smoking-induced differential gene expression changes in buccal mucosa
A tissue like buccal mucosa (from cheek swabs) would be an ideal sample material for rapid, easy collection for testing of biomarkers as an alternative to blood. A limited number of studies, primarily in the smoker/oral cancer literature, address this tissue's efficacy for quantitative PCR or micro...
ORGANISM(S): Homo sapiens 
2010-03-07 | E-GEOD-16149 | biostudies-arrayexpress
UnknownSpontaneous alloying of ultrasmall non-stoichiometric Ag-In-S and Cu-In-S quantum dots in aqueous colloidal solutions.
Not available
S-EPMC9034144 | biostudies-literature
TranscriptomicsGrowth-rate dependency of de novo resveratrol production in chemostat cultures of an engineered Saccharomyces cerevisiae strain
Saccharomyces cerevisiae has become a popular host for production of non-native compounds. The metabolic pathways involved generally require a net input of energy. To maximize the ATP yield on sugar in S. cerevisiae, industrial cultivation is typically performed in aerobic, sugar-limited fed-batch r...
ORGANISM(S): Saccharomyces cerevisiae 
2015-12-22 | E-GEOD-65942 | biostudies-arrayexpress
TranscriptomicsSevere alkaline pH stress induces a glucose starvation-related transcriptional response in S. cerevisiae
Alkaline pH stress invokes in S. cerevisiae a potent and fast transcriptional response that includes many genes repressed by glucose. Certain mutants in the glucose-sensing and response pathways, such as those lacking the Snf1 kinase, are sensitive to alkalinization. We show that addition of glucose...
ORGANISM(S): Saccharomyces cerevisiae 
2012-03-02 | E-GEOD-25697 | biostudies-arrayexpress
TranscriptomicsS. cerevisiae time-course in the presence of 100uM BCS
Saccharomyces cerevisiae cells were exposed to a copper chelator (100uM BCS) for 48 hours. Samples were compared to the zero hour timepoint at 0.5, 1, 2, 3, 4, 24 and 48 hours.
ORGANISM(S): Saccharomyces cerevisiae 
2006-04-03 | E-UMCU-16 | biostudies-arrayexpress
TranscriptomicsFunctional annotation of S. bayanus using a gene expression compendium
Technological advances now make gene expression analysis feasible in any sequenced organism, and new sequencing methods have greatly accelerated genome sequencing. Here we show that important insights into gene function are possible by comparing gene expression response to genetic and environmental...
ORGANISM(S): Saccharomyces bayanus 
2010-05-16 | E-GEOD-16544 | biostudies-arrayexpress
TranscriptomicsTRANSCRIPTIONAL REMODELLING IN RESPONSE TO CHANGING COPPER LEVELS IN WILSON DISEASE MODEL OF SACCHAROMYCES CEREVISIAE
A 3 x 2 factorial design was used to elucidate the genome-wide transcriptional response to the deletion of yeast ortholog of Wilson and Menkes disease causing gene; CCC2, at changing copper levels. Homozygous deletion mutant of CCC2, which encodes Cu+2 transporting P-type ATPase required to export c...
ORGANISM(S): Saccharomyces cerevisiae 
2013-09-02 | E-MEXP-3927 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of fission yeast in response to changes in copper and iron levels
Recent studies in comparative genomics demonstrate that inter-species comparisons represent a powerful tool for revealing both conserved and specialized biological processes across large evolutionary distances. All cells need to adjust to environmental fluctuations in metal levels since both metal ...
ORGANISM(S): Schizosaccharomyces pombe 
2007-03-01 | E-TABM-120 | biostudies-arrayexpress
TranscriptomicsThe effect of the magnesium and copper supplementation in the transcriptional response of Saccharomyces cerevisiae JP1 under fermentation condition
In our previous work, we showed the positive effect of the magnesium and the negative effect of the copper on yeast fermentation performance. The magnesium increases the ethanol yield and a faster glucose consumption by the yeast, on the other hand, the copper provides an opposite effect in yeast un...
ORGANISM(S): Saccharomyces cerevisiae 
2015-12-09 | E-GEOD-75803 | biostudies-arrayexpress
TranscriptomicsMicroarray characterization of gene expression changes in blood during acute ethanol exposure
As part of the civil aviation safety program to define the adverse effects of ethanol on flying performance, we present results of our DNA microarray analysis of samples from a timecourse study of individuals given ethanol orally, and then evaluated by breathalyzer to monitor blood alcohol content (...
ORGANISM(S): Homo sapiens 
2013-07-25 | E-GEOD-20489 | biostudies-arrayexpress
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