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TranscriptomicsTranscription profiling of fission yeast to investigate the role of the TORC2 complex in gene expression, DNA metabolism and damage response
Investigating the role of TORC2 complex in gene expression, DNA meatbolism and DNA damage response
ORGANISM(S): Schizosaccharomyces pombe 
2009-07-01 | E-MTAB-39 | biostudies-arrayexpress
TranscriptomicsIsp7 is a novel regulator of amino acid uptake in the TOR signaling pathway
We show that the sensitivity of tsc mutant cells to rapamycin is mediated by TORC1 and can be suppressed by overexpression of the 2-oxoglutarate-Fe(II) dependent oxygenase, Isp7. We show that Isp7 is a novel regulator of amino acids uptake that acts via regulation of gene expression, both upstream a...
ORGANISM(S): Schizosaccharomyces pombe 
2014-02-05 | E-GEOD-52759 | biostudies-arrayexpress
UnknownSystematic identification and correction of annotation errors in the genetic interaction map of Saccharomyces cerevisiae.
Not available
S-EPMC4797274 | biostudies-literature
UnknownTight Regulation of Srs2 Helicase Activity Is Crucial for Proper Functioning of DNA Repair Mechanisms.
Not available
S-EPMC5940153 | biostudies-literature
UnknownRole of the ESCRT Complexes in Telomere Biology.
Not available
S-EPMC5101353 | biostudies-literature
UnknownA New Method, "Reverse Yeast Two-Hybrid Array" (RYTHA), Identifies Mutants that Dissociate the Physical Interaction Between Elg1 and Slx5.
Not available
S-EPMC5500160 | biostudies-literature
UnknownTelomere length kinetics assay (TELKA) sorts the telomere length maintenance (tlm) mutants into functional groups.
Not available
S-EPMC4041441 | biostudies-literature
TranscriptomicsGene expression profiles of WT and ime4-/- mutant yeast cells, under vegetative and meiosis-inducing conditions
Inactivation of the yeast IME4 gene, the yeast homologue of METTL3, was shown to result in the loss of m6A in mRNA of mutant cells grown in sporulation medium. We attempted to characterize the effects of ime4 deletion on gene expression under vegetative and meiosis-inducing conditions. The results ...
ORGANISM(S): Saccharomyces cerevisiae 
2012-04-24 | E-GEOD-36958 | biostudies-arrayexpress
UnknownGWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19.
Not available
S-EPMC10208981 | biostudies-literature
UnknownA second update on mapping the human genetic architecture of COVID-19.
Not available
S-EPMC10482689 | biostudies-literature
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