Sort   by:  
 Page size 
TranscriptomicsTranscriptomic analysis reveals novel long non-coding RNAs critical for vertebrate development [Illumina]
Long non-coding RNAs (lncRNAs) have emerged as critical regulators of gene expression and chromatin modifications, with important functions in development and disease. Here we sought to identify and functionally characterize lncRNAs critical for vascular vertebrate development with significant conse...
ORGANISM(S): Homo sapiens 
2015-05-15 | E-GEOD-54966 | biostudies-arrayexpress
TranscriptomicsTranscriptomic analysis reveals novel long non-coding RNAs critical for vertebrate development [RNA-Seq]
Long non-coding RNAs (lncRNAs) have emerged as critical regulators of gene expression and chromatin modifications, with important functions in development and disease. Here we sought to identify and functionally characterize lncRNAs critical for vascular vertebrate development with significant conse...
ORGANISM(S): Homo sapiens 
2015-05-15 | E-GEOD-54968 | biostudies-arrayexpress
TranscriptomicsTranscriptomic analysis reveals novel long non-coding RNAs critical for vertebrate development [Affymetrix]
Long non-coding RNAs (lncRNAs) have emerged as critical regulators of gene expression and chromatin modifications, with important functions in development and disease. Here we sought to identify and functionally characterize lncRNAs critical for vascular vertebrate development with significant conse...
ORGANISM(S): Homo sapiens 
2015-05-15 | E-GEOD-54964 | biostudies-arrayexpress
ProteomicsTranslational specialization in pluripotency by RBPMS poises future lineage-decisions
Total proteome for triplicates of WT and RBPMS KO hESCs to identify differences in proteins abundances due to a loss of RBPMS. Cells were lysed and prepared according to the in solution digest protocol and 50 µg proteins were reduced, alkylated and digested with Lys-C and trypsind.
ORGANISM(S): Homo sapiens (Human) 
2023-05-10 | PXD032045 | Pride
Pluripotency Active-ribosome associated proteins Exit of pluripotency Rbpms 
ProteomicsTranslational specialization in pluripotency by RBPMS poises future lineage-decisions
Labeling active ribosome associated proteins by L-Azidohomoalanine (AHA)- pulldown. Humane embryonic stem cells were labeled via AHA in methionine-free medium for 40 min. AHA labeled nascent proteins together with ribosomes and associated proteins were isolated with beads. Samples were divided into ...
ORGANISM(S): Homo sapiens (Human) 
2023-10-26 | PXD032046 | Pride
Pluripotency Active-ribosome associated proteins Exit of pluripotency Rbpms 
TranscriptomicsRecapitulation of human premature aging by using iPSCs from Hutchinson-Gilford progeria syndrome
Hutchinson-Gilford progeria syndrome (HGPS) is a rare and fatal human premature aging disease1-5, characterized by premature atherosclerosis and degeneration of vascular smooth muscle cells (SMCs)6-8. HGPS is caused by a single-point mutation in the LMNA gene, resulting in the generation of progerin...
ORGANISM(S): Homo sapiens 
2011-03-14 | E-GEOD-24487 | biostudies-arrayexpress
TranscriptomicsGene expression from lamina propria of olfactory mucosa from Human
The establishment of induced pluripotent stem (iPS) cells methodologies has widened the possibilities of stem cell related clinical therapies. However, safety concerns over current reprogramming technologies as well as lack of efficient protocols for differentiation raise serious questions over thei...
ORGANISM(S): Homo sapiens 
2012-11-15 | E-GEOD-25336 | biostudies-arrayexpress
TranscriptomicsConversion of human fibroblasts into vascular cells (methylation)
We report a novel technique to reprogram human fibroblasts into endothelial and smooth muscle cells using partial iPSC reprogramming and chemically defined media. Using appropriate media conditions for differentiation of human pluripotent cells to CD34+ vascular progenitor cells, we show that tempor...
ORGANISM(S): Homo sapiens 
2012-09-18 | E-GEOD-40909 | biostudies-arrayexpress
UnknownCombined Associations of a Polygenic Risk Score and Classical Risk Factors With Breast Cancer Risk.
Not available
S-EPMC7936056 | biostudies-literature
UnknownFunctional annotation of the 2q35 breast cancer risk locus implicates a structural variant in influencing activity of a long-range enhancer element.
Not available
S-EPMC8322933 | biostudies-literature
Sort   by:  
 Page size