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ProteomicsLinking acetyl-CoA labelling and histone acetylation dynamics for accurate determination of acetylation rates via ordinary differential equations
To study complex biological systems, multi-omics methods have become an important tool. They integrate data from multiple biological layers, such as the metabolome and the proteome, to gain better insights of the processes happening. However, challenges remain both in sample preparation for measurem...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD051487 | Pride
Human Lc-msms Acetylcoa Ptm Histone Acetylation Hek93t 
ProteomicsCombined Metabolic and Chemical (CoMetChem) labeling using stable isotopes
Histone acetylation is an important, reversible posttranslational protein modification and hallmark of epigenetic regulation. However, little is known about the dynamics of reversible hisotne acetylation, due to the lack of analytical methods that can capture site-specific acetylation and deacetylat...
ORGANISM(S): Mus musculus (Mouse) 
2021-11-02 | PXD027338 | Pride
Lc-msms Stable isotopes Acetylation Histones 
GenomicsConjunctival fibrosis and the innate barriers to Chlamydia trachomatis intracellular infection: a genome wide association study
This data comes from a genome-wide association study in 1090 cases of scarring trachoma and 1531 controls from a non-selected multi-ethnic sampling of The Gambia. The data constitutes hard base calls at 1457295 features from the HumanOmni2.5-8 (Omni2.5) BeadChip. Three genotype-calling algorithms we...
EGAS00001001516 | EGA
GenomicsLow_coverage_sequencing_of_the_Woloff_from_Gambia_Western_Division__GWW_
Low_coverage_sequencing_of_the_Woloff_from_Gambia_Western_Division__GWW_
PRJEB1323 | ENA
GenomicsLow_coverage_sequencing_of_the_Mandinka_from_Gambia_Western_Division__GWD_
Low_coverage_sequencing_of_the_Mandinka_from_Gambia_Western_Division__GWD_
PRJEB1682 | ENA
GenomicsLow_coverage_sequencing_of_the_Fula_from_Gambia_Western_Division__GWF_
Low_coverage_sequencing_of_the_Fula_from_Gambia_Western_Division__GWF_
PRJEB3013 | ENA
GenomicsLow_coverage_sequencing_of_the_Jola_from_Gambia_Western_Division__GWJ_
Low_coverage_sequencing_of_the_Jola_from_Gambia_Western_Division__GWJ_
PRJEB3252 | ENA
UnknownTXNIP mediates LAT1/SLC7A5 endocytosis to limit amino acid uptake in cells entering quiescence
Not available
S-SCDT-10_1038-S44318-025-00608-9 | biostudies-other
GenomicsTrachoma_GWAS_Unscarred_Controls
Gambian specimens with trachomatous scarring WHO grade C2/C3
EGAD00010000940 | EGA
GenomicsTrachoma_GWAS_Scarred_Cases
Gambian specimens without trachomatous scarring
EGAD00010000941 | EGA
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