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TranscriptomicsA dysregulated Acetyl/SUMO switch of FXR promotes hepatic inflammation in obesity
Acetylation of transcriptional regulators is normally dynamically regulated by nutrient status but is often persistently elevated in nutrient-excessive obesity conditions. We investigated the functional consequences of such aberrantly elevated acetylation of the nuclear receptor FXR as a model. Prot...
ORGANISM(S): Mus musculus 
2014-10-17 | E-GEOD-62414 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of GFP-positive cancer stem-like cells(CSLC) derived from MDA-MB453 cells, compared with GFP-negative non-cancer stem cells (non-CSLC).
Analysis of genes that differentially expressed in CSLC cells compared with non-CSLC cells, which are derived from the same parental MDA-MB453 cell line. Total RNAs were isolated from two pairs of GFP-positive CSLCs (ST1, ST2) and GFP-negative non-CSLCs (NS1, NS2) on different days. Two batches of R...
ORGANISM(S): Homo sapiens 
2013-02-01 | E-GEOD-43336 | biostudies-arrayexpress
TranscriptomicsGene expression profiles in the spinal cord below the lesion level and influence of treadmill locomotor training
Traumatic spinal cord injury (SCI) often leads to loss of locomotor function. Neuroplasticity of spinal circuitry underlies some functional recovery and therefore represents a therapeutic target to improve locomotor function following SCI. However, the cellular and molecular mechanisms mediating neu...
ORGANISM(S): Rattus norvegicus 
2013-11-27 | E-GEOD-52763 | biostudies-arrayexpress
UnknownA graphene-based platform for the assay of duplex-DNA unwinding by helicase.
Not available
S-EPMC7159720 | biostudies-literature
UnknownBafilomycin A1 induces colon cancer cell death through impairment of the endolysosome system dependent on iron.
Not available
S-EPMC11814099 | biostudies-literature
UnknownA Graphene-Based Platform for the Assay of Duplex-DNA Unwinding by Helicase.
Not available
S-EPMC7159641 | biostudies-literature
UnknownGlutathione Induced Immune-Stimulatory Activity by Promoting M1-Like Macrophages Polarization via Potential ROS Scavenging Capacity.
Not available
S-EPMC6770173 | biostudies-literature
UnknownEffects of Lespedeza Cuneata aqueous extract on testosterone-induced prostatic hyperplasia.
Not available
S-EPMC6366415 | biostudies-literature
UnknownThe effect of maslinic acid on cognitive dysfunction induced by cholinergic blockade in mice.
Not available
S-EPMC7312314 | biostudies-literature
UnknownMDM2 E3 ligase-mediated ubiquitination and degradation of HDAC1 in vascular calcification.
Not available
S-EPMC4740400 | biostudies-literature
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