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MetabolomicsTrans-tissue molecular coordination in high-intensity physical activity
High-intensity physical activity has major impacts in different parts of the body. However, the regulatory coordination between different tissues to support the high physical demands is poorly understood. Here we performed a multi-omics analysis of blood plasma, urine and saliva from a group of fire...
2025-07-03 | MTBLS1891 | MetaboLights
ProteomicsMulti-Omic Evidence of Brain Region Specific APOE Genotype Perturbations in Alzheimer's Disease
Simultaneous extraction of proteins and lipids from human frontal cortex and cerebellum brain tissue was performed using the MPLEx procedure for both control and Alzheimer's disease patients. The isolated proteins were then reduced, alkylated, tryptically digested and evaluated with LC-IMS-MS. The p...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-08-08 | MSV000092627 | MassIVE
ProteomicsCharactering the lipidome of Huh7 Zika infected cells at 24hpi and 48hpi
Lipidomic analysis of Huh7 cells infected with Zika FSS13025 at an MOI of ~10. Samples collected at 24 and 48 hrs post infection.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-10-29 | MSV000083079 | MassIVE
MetabolomicsGNPS A global lipid map reveals host dependency factors conserved across SARS-CoV-2 variants
Using non-targeted LC-MS/MS lipidomics approaches, we profiled SARS-CoV-2 changes in cellular lipid composition for both 293T HEK infected cells and cells ectopically expressing individual SARS-CoV-2 proteins, in total examining 26 experimental conditions and three control conditions, each in biolog...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-08-04 | MSV000087944 | GNPS
MetabolomicsGNPS - A global lipid map defines a network essential for Zika virus replication
Zika virus (ZIKV), an arbovirus of global concern, remodels intracellular membranes to form replication sites. We performed comprehensive lipidomics to create a lipid network map during ZIKV infection. We found that ZIKV significantly alters host lipid composition, with the most striking changes see...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-06-15 | MSV000085584 | GNPS
MetabolomicsGNPS - Charactering the lipidome of Huh7 Zika infected cells at 24hpi and 48hpi
Lipidomic analysis of Huh7 cells infected with Zika FSS13025 at an MOI of ~10. Samples collected at 24 and 48 hrs post infection.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-10-29 | MSV000083079 | GNPS
ProteomicsFrom plants to ants: Evaluating lipidomic changes in leaf-cutter ant fungus gardens
Leaf-cutter ants use fresh plant material to cultivate an obligate mutualistic fungus Leucoagaricus gongylophorus in specialized fungus gardens to access and transform nutrients from plant biomass that would otherwise be unavailable to the ants. Here, we evaluated the lipidomic differences between t...
ORGANISM(S): Environmental Samples <bacteria> (ncbitaxon:48479) 
2019-10-30 | MSV000084520 | MassIVE
Proteomics,MultiomicsLIQUID publication data - human plasma lipids
These files are associated with the publication of the LIQUID identification tool for lipid MS/MS spectra.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-11-28 | MSV000080359 | MassIVE
MetabolomicsGNPS - Multi-Omic Evidence of Brain Region Specific APOE Genotype Perturbations in Alzheimer's Disease
Simultaneous extraction of proteins and lipids from human frontal cortex and cerebellum brain tissue was performed using the MPLEx procedure for both control and Alzheimer's disease patients. The isolated proteins were then reduced, alkylated, tryptically digested and evaluated with LC-IMS-MS. The p...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-08-08 | MSV000092627 | GNPS
MetabolomicsIntegrated omics analysis of pathogenic host responses during pandemic H1N1 influenza virus infection: the crucial role of lipid metabolism
Pandemic influenza viruses modulate pro-inflammatory responses that can lead to immunopathogenesis. We present an extensive and systematic profiling of lipids, metabolites and proteins in respiratory compartments of ferrets infected with either 1918 or 2009 human pandemic H1N1 influenza viruses. Int...
2016-05-11 | MTBLS196 | MetaboLights
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