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TranscriptomicsM. sedula transcriptional response under "strict" carbon-limited autotrophy compared to carbon "rich" autotrophy and heterotrophy
Metallosphaera sedula is an extremely thermoacidophilic archaeon that grows heterotrophically on peptides, and chemolithoautotrophically on hydrogen, sulfur, or reduced metals as energy sources. During autotrophic growth, carbon dioxide is incorporated into cellular carbon via the 3-hydroxypropionat...
ORGANISM(S): Metallosphaera sedula DSM 5348 
2013-03-05 | E-GEOD-39944 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human soluble guanylate cyclase-deficient U937 cells exposed to the nitric oxide (NO) donor S-nitrosoglutathione to provide insight into the cGMP-independent effects of NO
NO effects on gene expression, independent of cGMP, were examined globally. Differentiated human U937 cells that lack soluble guanylate cyclase were exposed to Snitrosoglutathione, a NO donor, or glutathione without or with dibutyryl-cAMP (Bt2cAMP). NO regulated 110 transcripts that annotated dispro...
ORGANISM(S): Homo sapiens 
2007-09-11 | E-GEOD-2649 | biostudies-arrayexpress
UnknownEpilepsy and neurobehavioral abnormalities in mice with a dominant-negative KCNB1 pathogenic variant.
Not available
S-EPMC7725922 | biostudies-literature
GenomicsDistinct epigenomic landscapes of pluripotent and lineage-committed human cells
Human embryonic stem cells share identical genomic sequences with other lineage-committed cells yet possess the remarkable properties of self-renewal and pluripotency. It has been proposed that epigenetic regulatory mechanisms, involving DNA methylation and various chromatin modifications, are at l...
ORGANISM(S): Homo sapiens 
2009-10-13 | E-GEOD-17917 | biostudies-arrayexpress
UnknownThe impact of genetic ancestry on survival outcomes in pediatric rhabdomyosarcoma: A report from the Children's Oncology Group.
Not available
S-EPMC12256324 | biostudies-literature
GenomicsChromatin States in Human ES Cells Reveal Key Regulatory Sequences and Genes Involved in Pluripotency and Self-renewal
Human embryonic stem cells (hESCs) are offering a new therapeutic approach because of their unique ability to proliferate indefinitely in vitro and differentiate into multiple cell types. However, our understanding of the molecular mechanisms of pluripotency and self-renewal remain incomplete. To el...
ORGANISM(S): Homo sapiens 
2009-10-14 | E-GEOD-18292 | biostudies-arrayexpress
UnknownExploring the Impact of Treatment Switching on Overall Survival from the PROfound Study in Homologous Recombination Repair (HRR)-Mutated Metastatic Castration-Resistant Prostate Cancer (mCRPC).
Not available
S-EPMC8484203 | biostudies-literature
UnknownLate Effects in Childhood Cancer Survivors: Early Studies, Survivor Cohorts, and Significant Contributions to the Field of Late Effects.
Not available
S-EPMC8393933 | biostudies-literature
UnknownClinical group and modified TNM stage for rhabdomyosarcoma: A review from the Children's Oncology Group.
Not available
S-EPMC9233945 | biostudies-literature
UnknownClinical Characteristics, Symptoms, and Long-Term Outcomes in Gitelman Syndrome.
Not available
S-EPMC12640036 | biostudies-literature
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