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TranscriptomicsComparison of the transcriptional profiles of male E13.5 wild type and L/H-Pgds-/- gonads
The goals of this study are to compare transcriptome profiling of L/H-Pgds-/- gonads to that of WT (RNA-seq) Methods: mRNA profiles of E13.5 wild-type (WT) and L- and H- prostaglandin D synthases (L/H-Pgds?/?) embryonic gonad were generated by deep sequencing, in triplicate, using Illumina HiSeq20...
ORGANISM(S): Mus musculus 
2014-08-26 | E-GEOD-55744 | biostudies-arrayexpress
GenomicsEffect of L-PGDS loss on cellular response during cuprizone induced demyelination
Effect of L-PGDS loss on cellular response during cuprizone induced demyelination
PRJNA1436470 | ENA
TranscriptomicsEffect of L-PGDS loss on cellular response during cuprizone induced demyelination
L-PGDS is a secretory oligodendrocyte protein; we aimed to determine how the loss of this protein affected the transcriptome of different cell populations during demyelination. We found that very distinct changes in the microglial transcriptome following L-PGDS loss. Specifically, these microglia ad...
ORGANISM(S): Mus musculus 
2026-03-20 | GSE324634 | GEO
TranscriptomicsExpression data from WT and L-PGDS ko mice aorta
We used microarray data to look for gene differentially expressed in the aorta of WT and L-PGDS ko male mice.
ORGANISM(S): Mus musculus 
2018-12-10 | GSE77642 | GEO
ProteomicsProteomics analysis of the corneal amyloid disaggregation effects by brain chaperone L-PGDS
TGFBIp-related corneal dystrophy (CD) is the most common form of stromal corneal dystrophy. Although CD is a group of inheritable and progressive corneal diseases, non-inheritable cases of corneal amyloid deposition are reported. TGFBIp-CD is characterized by the accumulation of insoluble protein de...
ORGANISM(S): Homo sapiens (Human) 
2023-05-10 | PXD038281 | Pride
Tgfbi-related corneal dystrophy L-pgds Amyloid disaggregation Corneal dystrophy Atp independent 
TranscriptomicsComparison of the transcriptional profiles of male E13.5 wild type and L/H-Pgds-/- gonads
The goals of this study are to compare transcriptome profiling of L/H-Pgds-/- gonads to that of WT (RNA-seq)
ORGANISM(S): Mus musculus 
2014-08-26 | GSE55744 | GEO
UnknownL-PGDS deficiency accelerated the development of naturally occurring age-related osteoarthritis.
Not available
S-EPMC7803483 | biostudies-literature
UnknownAbundant neuroprotective chaperone Lipocalin-type prostaglandin D synthase (L-PGDS) disassembles the Amyloid-β fibrils.
Not available
S-EPMC6715741 | biostudies-literature
UnknownAnticholinergic Drugs Interact With Neuroprotective Chaperone L-PGDS and Modulate Cytotoxicity of Aβ Amyloids.
Not available
S-EPMC7300299 | biostudies-literature
GenomicsMus musculus
Expression data from WT and L-PGDS ko mice aorta
PRJNA311073 | ENA
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