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TranscriptomicsTranscriptomic profiling of L-rhamnose utilization in Lmo0753 deletion mutant of Listeria monocytogenes EGDe from human foodborne outbreak associated lineage LII
Among the three major genetic lineages of L. monocytogenes (i.e. LI, LII, and LIII), LI and LII are predominantly associated with foodborne listeriosis outbreaks, whereas LIII is rarely implicated in human infections. In a previous study, we identified a Crp/Fnr family transcription factor lmo0753 t...
ORGANISM(S): Listeria monocytogenes 
2013-07-17 | E-GEOD-47721 | biostudies-arrayexpress
TranscriptomicsSigma B in Listeria monocytogenes strains from different lineages
Listeria monocytogenes strains classify into at least three distinct phylogenetic lineages. Correlations exist between lineage classification and source of bacterial isolation, e.g., human clinical and food isolates usually classify into either lineage I or II, however, human clinical isolates are ...
ORGANISM(S): Listeria monocytogenes 
2010-06-01 | E-GEOD-21427 | biostudies-arrayexpress
TranscriptomicsProbing the pan genome of a foodborne bacterial pathogen Listeria monocytogenes
Full title: Probing the pan genome of a foodborne bacterial pathogen Listeria monocytogenes: Implications for its niche adaptation, pathogenesis, and evolution Listeria monocytogenes is a foodborne bacterial pathogen well known for adaptability to diverse environmental and host niches, and a high f...
ORGANISM(S): Listeria monocytogenes EGD-e 
2010-04-06 | E-GEOD-20367 | biostudies-arrayexpress
TranscriptomicsModulation of PrfA activity in Listeria monocytogenes upon growth in different culture media
PrfA activity was studied in L. monocytogenes strain EGD and in an isogenic prfA deletion mutant (EGDΔprfA) carrying multiple copies of the wild-type prfA or the mutant prfA* gene (strains EGDΔprfApPrfA and EGDΔprfApPrfA*) after growth in brain heart infusion (BHI), Luria-Bertani broth (LB) or a def...
ORGANISM(S): Listeria monocytogenes 
2008-11-30 | E-GEOD-12151 | biostudies-arrayexpress
TranscriptomicsIdentification of sigB inhibitors in L. monocytogenes
The extensively studied intracellular pathogen, L. monocytogenes, is an ideal model for identifying small-molecule agents for treating bacterial infections. By selecting specific biological targets in L. monocytogenes, which are common to Gram-positive pathogens, we could extrapolate drug discovery ...
ORGANISM(S): Listeria monocytogenes 10403S 
2011-12-06 | E-GEOD-16887 | biostudies-arrayexpress
TranscriptomicsCharacterization of the SigB-PrfA regulatory network in Listeria monocytogenes
Listeria monocytogenes SigB and PrfA are pleiotropic regulators of stress response and virulence gene expression, which have been shown to co-regulate genes in L. monocytogenes. We performed whole genome transcriptional profiling in the presence of PrfA* and active SigB, to identify the overlaps be...
ORGANISM(S): Listeria monocytogenes 
2010-05-19 | E-GEOD-11347 | biostudies-arrayexpress
TranscriptomicsGlobal Transcriptional Analysis of Spontaneous Sakacin P-Resistant Mutant Strains of Listeria monocytogenes during Growth on Different Sugars
Subclass IIa bacteriocins have strong antilisterial activity and can control the growth of Listeria monocytogenes in food. However, L. monocytogenes may develop resistance towards such bacteriocins. In this follow-up study, the transcriptomes of a high level (L502-1) and a low level (L502-6) spontan...
ORGANISM(S): Listeria monocytogenes 
2011-04-15 | E-BUGS-110 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of a pressure-tolerant Listeria monocytogenes Scott A ctsR deletion mutant
Transcriptional profling of a Listeria monocytogenes under pressure comparing ctsR mutant and wild type one condition (pressure 450 Moa, 3min) experiment, mutant vs. wild type, 2 biological replicates, two technical replicates
ORGANISM(S): Listeria monocytogenes 
2011-06-10 | E-GEOD-22819 | biostudies-arrayexpress
TranscriptomicsTranscriptional adaptation of L. monocytogenes EGD to oxygen availability
Comparison of aerobic and anaerobic transcriptome of L. monocytogenes EGD L. monocytogenes EGD cells used in this study were grown either aerobically or anaerobically to an OD600 = 0.70 - 0.75 and the transcriptome of these two conditions was compared Six biologically independent cultures of each ae...
ORGANISM(S): Listeria monocytogenes EGDe 
2014-01-27 | E-GEOD-52325 | biostudies-arrayexpress
TranscriptomicsGene expression of Listeria monocytogenes-infected HepG2 hepatocellular carcinoma in the presense of IL-17Aand IL-22
IL-17A and IL-22 induced several inflammation-induced genes and anti-microbial molecules including Pla2g2a and Lcn2 on HepG2 cells when the cells were treated with the cytokines before Listeria monocytogenes infection. HepG2 cells were treated with 50 ng/ml IL-17A and 10 ng/ml IL-22 before L. monocy...
ORGANISM(S): Homo sapiens 
2015-12-17 | E-GEOD-71248 | biostudies-arrayexpress
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