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Microarray expression profilling of mouse primary mixed cortical/hippocampal neurons, primary fibroblasts and L929 cells to compare ISGs signature in disctinct cell types Primary mixed cortical/hippocampal neurons, primary fibroblasts (MEFs) and L929 cells were mock-treated or treated with 5U/mL of ...
ORGANISM(S): Mus musculus 
Bone marrow-derived macrophages (BMDMs) are a key model system for studying macrophage biology in vitro. Commonly used methods to differentiate macrophages from bone marrow are treatment with either recombinant M-CSF or the supernatant of L929 cells, which secrete M-CSF. However, little is known abo...
ORGANISM(S): Mus musculus (Mouse) 
2021-04-13 | PXD021026 | Pride
Mus musculus strain:C3H/An | isolate:L929 Raw sequence reads
We used microarrays to find Stat6 dependent genes in control and IL-4 exposed bone marrow derived macrophages. Alternatively activated macrophages (AAM) accumulate in tissues during Th2-associated immune responses like helminth infections and allergic disorders. These cells possess potent inhibitor...
ORGANISM(S): Mus musculus 
This study aimed to characterize global proteome changes induced by MDM2 knockdown in L929 mouse fibroblast cells. Whole-cell lysates from mock-treated control cells and MDM2 knockdown cells were subjected to label-free quantitative proteomic analysis using high-resolution LC–MS/MS. The resulting da...
ORGANISM(S): Mus Musculus 
2026-03-04 | PXD075242 |
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