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TranscriptomicsGlobal expression analysis of HNF4alpha and HNFgamma-mediated transcriptional control
Hepatocyte nuclear factor-4α (HNF4α, NR2A1) is a nuclear receptor which has a critical role in hepatocyte differentiation and the maintenance of homeostasis in the adult liver. However, a detailed understanding of native HNF4α in the steady state remains to be elucidated. Here we report the native H...
ORGANISM(S): Homo sapiens 
2010-12-22 | E-GEOD-18973 | biostudies-arrayexpress
ProteomicsLabel-free quantitative proteomics in Candida yeast species: technical and biological replicates to asses data reproducibility
Objective Label-free quantitative proteomics has emerged as a powerful strategy to obtain high quality quantitative measures of the proteome with only a very small quantity of total protein extract. Because our research projects were requiring the application of bottom-up shotgun Mass Spectrometry p...
ORGANISM(S): Candida albicans (Yeast) Candida glabrata (Yeast) (Torulopsis glabrata) 
2019-07-08 | PXD014125 | Pride
Mass spectrometry  label-free quantitative proteomics  candida glabrata  candida albicans  alkaline ph 
ProteomicsBlack pepper proteome - Transcriptome- Assisted Label-Free Quantitative Proteomics Analysis Reveals Novel Insights into Piper nigrum-Phytophthora capsici Phytopathosystem
In this study, we have evaluated the proteomic changes that occur in Piper nigrum L.(black pepper) after infection by the pathogen Phytophthora capsici. We report novel leaf proteins from black pepper identified by an integrated transcriptome-assisted label-free quantitative proteomics pipeline. Sev...
ORGANISM(S): Piper nigrum 
2016-07-07 | PXD003887 | Pride
Plgs Label-free quantitative proteomics Piper nigrum 
ProteomicsAn Integrated Quantitative Proteomics Workflow for Biomarker Discovery and Validation in Plasma
Blood plasma is one of the most widely used samples for biomarker discovery research as well as clinical investigations for diagnostic and therapeutic purposes. However, the plasma proteome is extremely complex due to its wide dynamic range of protein concentrations and the presence of high-abundanc...
ORGANISM(S): Homo sapiens (Human) 
2020-09-07 | PXD017834 | Pride
Targeted proteomics Label-based quantitation Label-free quantitation 
ProteomicsLabel-free Quantitative Proteomics Identifies Novel Plasma Biomarkers for Distinguishing Pulmonary Tuberculosis and Latent Infection
Lack of effective differential diagnostic methods between active tuberculosis (TB) and latent infection (LTBI) is still an obstacle for TB control. Furthermore, the molecular mechanism behind the progression from LTBI to active TB has been not elucidated until now. Therefore, we performed label-free...
ORGANISM(S): Homo Sapiens 
2024-09-20 | PXD056149 |
UnknownApplying label-free quantitation to top down proteomics.
Not available
S-EPMC4033644 | biostudies-literature
ProteomicsLabel-free quantification in ion-mobility enhanced data-independent acquisition proteomics
Data-dependent acquisition (DDA) methods are a well-established tool for proteome analysis and have greatly expedited the field of shotgun proteomics. However, their serial and stochastic nature restricts their reproducibility and limits the detectable dynamic range to the peptides that ionize best....
ORGANISM(S): Homo sapiens (Human) Saccharomyces cerevisiae (strain Lalvin EC1118 / Prise de mousse) (Baker's yeast) Escherichia coli 
2016-03-29 | PXD002393 | Pride
Proteomics Mass spectrometry Label-free quantification Ion mobility separation Data-independent acquisition 
UnknownA label-free quantitative shotgun proteomics analysis of rice grain development.
Not available
S-EPMC3190340 | biostudies-literature
ProteomicsQuantitative Label-free Comparison of the Metabolic Protein Fraction in Old and Modern Wheat Italian Genotypes by a Shotgun Approach
Wheat represents one of the most important cereals for mankind. However, since wheat proteins are also the causative agent of several adverse reactions, during the last decades, consumers have shown an increasing interest in the old wheat genotypes, which are generally perceived as more “natural” an...
ORGANISM(S): Triticum aestivum (Wheat) 
2021-05-13 | PXD024204 | Pride
Old and modern wheat genotypes  label-free quantitation  high-resolution mass spectrometry  proteome analysis  metabolic proteins 
ProteomicsQuantitative Label Free Ultra Definition Mass-Spectrometry Provides Novel Data on the Proteomic Signature of Oral Squamous Cell Carcinoma
There are no early detection biomarkers or prognostic markers for oral squamous cell carcinoma (OSCC) thus many are detected late, with unpredictable disease course. Using systems level analysis on shotgun proteomics with quantitative label-free ultra-definition mass spectrometry, our study aims to ...
ORGANISM(S): Homo sapiens (Human) 
2022-03-02 | PXD009244 | Pride
Oscc Tongue cancer Label-free proteomics Tissue proteomics 
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