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MetabolomicsNon-targeted metabolomics sequencing of Lactobacillus salivarius fermentation broth
To conduct an in-depth analysis of which metabolites in the antiviral-effective lactic acid bacteria supernatant are playing a role, a pretreatment approach was selected. Non-targeted metabolomic analysis was performed on the differential metabolites between LSD2339-CFS and LSM231-CFS, which exhibit...
2026-06-08 | MTBLS14704 | MetaboLights
MetabolomicsMetabolomic Profiling of Oxalate-Degrading Probiotic Lactobacillus acidophilus and Lactobacillus gasseri
Not available
ORGANISM(S): Lactobacillus 
ST001263 | MetabolomicsWorkbench
MetabolomicsLactobacillus johnsonii-derived oxindole protects acute lung injury by reducing CXCL13
Gut microbiota is altered in mice with acute lung injury (ALI). Supplementation with Lactobacillus johnsonii, which is deficient in it, improved ALI in mice, and we elucidated the underlying mechanisms of the improvement by metabolomics.
2026-02-12 | MTBLS11438 | MetaboLights
MetabolomicsLactobacillus reuteri bile acid metabolism in vitro

Upon reaching an OD600 of 0.3, L.

reuteri cultures were treated with 100 µM TCA, HCA, or

TCDCA. For BSHs inhibition assays, additional wells were treated with 100 µM

HCA + GR7. Both negative control and MRS medium control groups were included.

Cultures were terminated at 7...

2025-07-04 | MTBLS12641 | MetaboLights
MetabolomicsLactobacillus plantarum MR1 alleviates high-carbohydrate diet-induced oxidative stress and liver lipid deposition via upregulating uridine synthesis
The overconsumption of carbohydrates induces oxidative stress and lipid accumulation in the liver, which can be alleviated by modulation of intestinal microbiota; however, the underlying mechanism remains unclear. Here, we demonstrated that a strain affiliated with Lactobacillus plantarum (de...
2024-01-16 | MTBLS4262 | MetaboLights
MetabolomicsChronic mild stress and Lactobacillus experiments on mice
Not available
ORGANISM(S): Mus musculus 
ST000296 | MetabolomicsWorkbench
MetabolomicsMetabolomics and Proteomics Reveal the Inhibitory Effect of Lactobacillus crispatus on Cervical Cancer Cells
Cervical cancer remains a significant global health issue due to its high morbidity and mortality rates. Recently, Lactobacillus crispatus has been recognized for its crucial role in maintaining cervical health. While some studies have explored the use of L. crispatus to mitigate cervical cancer, th...
2024-09-05 | MTBLS10498 | MetaboLights
MetabolomicsLactobacillus rhamnosus B16 Regulates Lipid Metabolism Homeostasis by Producing Acetic Acid

Background Hyperlipidemia, a chronic disorder caused by abnormal lipid metabolism, increases risks of atherosclerosis and cardiovascular diseases. 

Current single-target drugs have limited efficacy and side effects, prompting interest in probiotics like Lactobacillus rhamnosus, though ...

2025-08-14 | MTBLS12858 | MetaboLights
TranscriptomicsComparative genome hybridization for Lactobacillus casei
Lactobacillus casei is remarkably adaptive to diverse habitats. To understand the evolution and adaptation of Lb. casei strains isolated from different environments, the gene content of 22 Lb. casei strains isolated from various habitats (cheeses, n=8; plant materials, n=8; and human sources, n=6) w...
ORGANISM(S): Lactobacillus casei 
2010-06-21 | E-GEOD-15030 | biostudies-arrayexpress
MetabolomicsLactobacillus reuteri DSM17938 and its supernatant ameliorate parkinson's disease: insights from multi-omics and network pharmacology

The mechanisms by which probiotics ameliorate neurodegenerative diseases have garnered significant scientific interest, yet elucidating their underlying pathways remains challenging. In this study, we establish an integrated multi-omics and network pharmacology strategy to unravel the prote...

2025-10-18 | MTBLS13169 | MetaboLights
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