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MetabolomicsLactobacillus johnsonii-derived oxindole protects acute lung injury by reducing CXCL13
Gut microbiota is altered in mice with acute lung injury (ALI). Supplementation with Lactobacillus johnsonii, which is deficient in it, improved ALI in mice, and we elucidated the underlying mechanisms of the improvement by metabolomics.
2026-02-12 | MTBLS11438 | MetaboLights
MetabolomicsMetabolomic and Proteomic Profiling of the Antimicrobial Potentials from Lactobacillus johnsonii KD1 Cell-Free Supernatant against Foodborne Pathogenic Bacteria

This study characterized functions and metabolic profiles of cell-free supernatants (CFS) from Lactobacillus johnsonii KD1 against three foodborne pathogens: the Gram-negative bacteria Vibrio parahaemolyticus 3HP and Salmonella enterica serovar ...

2026-09-24 | MTBLS14550 | MetaboLights
MetabolomicsBacteroides uniformis degrades β-glucan to promote Lactobacillus johnsonii improving indole-3-lactic acid levels in alleviating colitis

The gut microbiota plays a crucial role in the onset and progression of inflammatory bowel disease (IBD). β-glucan (BG), a soluble dietary fiber widely present in oats, barley, fungi, yeast and some bacteria, has multiple bioactive properties such as mitigating intestinal inflammation; however, t...

2024-02-12 | MTBLS8950 | MetaboLights
TranscriptomicsLactobacillus johnsonii NCC comparative genomics with L. iatae
Whole genome DNA microarray designed for the probiotic L. johnsonii strain NCC533 was used for comparative genomic hybridization (CGH) of L. johnsonii ATCC 33200T, L. johnsonii BL261, L. gasseri ATCC 33323T and L. iatae BL263 (CECT 7394T). In these experiments, the fluorescence ratio distributions o...
ORGANISM(S): Lactobacillus johnsonii 
2010-11-24 | E-GEOD-21627 | biostudies-arrayexpress
ProteomicsLactobacillus johnsonii N6.2 Compartive Proteomics LC-MS/MS
Comparative analysis between the protein composition of L. johnsonii N6.2's cell membrane and nanovesicle.
ORGANISM(S): Lactobacillus johnsonii N6.2 
2021-08-24 | PXD027785 | Pride
Extracellular vesicles  nanovesicles  lactobacillus johnsonii n6.2  probiotic  proteomics  cell membrane 
ProteomicsAn animal-free medium enhances Lactobacillus johnsonii LJO02 supernatant selective efficacy against the methicillin (oxacillin)-resistant Staphylococcus aureus virulence through key-metabolites
The spread of multidrug-resistant (MDR) bacteria, such as the skin commensal Staphylococcus aureus, is a worldwide heath challenge; therefore, new methods to counteract the over-colonization and virulence of opportunistic pathogenic biotypes are highly urgent. We characterized and compared the acti...
ORGANISM(S): Lactobacillus johnsonii Lacticaseibacillus rhamnosus 
2022-06-09 | PXD030916 | Pride
Lacticaseibacillus rhamnosus Scfas Cell-free supernatants Lactobacillus johnsonii Proteimics Staphylococcus aureus 
GenomicsLactobacillus johnsonii
Lactobacillus johnsonii Genome sequencing
PRJNA1004238 | ENA
GenomicsLactobacillus johnsonii
Lactobacillus johnsonii Genome sequencing
PRJNA1020604 | ENA
GenomicsLactobacillus johnsonii
Lactobacillus johnsonii Genome sequencing and assembly
PRJNA316010 | ENA
GenomicsLactobacillus johnsonii pf01
Lactobacillus johnsonii pf01 genome sequencing
PRJNA67469 | ENA
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