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TranscriptomicsAn oncogenic Kras expression signature identified by cross-species
Mouse lung cancers were generated using the KrasLA model, in which a latent mutated Kras2 allele (resulting in the amino acid substitution G12D) is sporadically activated through spontaneous homologous recombination. These mice develop lung adenomas with full penetrance; over time, the tumors acquir...
ORGANISM(S): Mus musculus 
2013-08-01 | E-GEOD-49200 | biostudies-arrayexpress
TranscriptomicsGene expression analysis in mice with heart muscle-specific repression of CELF activity (MHC-CELFdelta)
Members of the CUG-BP, Elav-like family (CELF) regulate alternative splicing in the heart. In MHC-CELFdelta transgenic mice, CELF splicing activity is inhibited postnatally in heart muscle via expression of a nuclear dominant negative CELF protein under an a-myosin heavy chain promoter. MHC-CELFde...
ORGANISM(S): Mus musculus 
2013-08-26 | E-GEOD-40677 | biostudies-arrayexpress
UnknownLacrimo-auriculo-dento-digital syndrome: A novel mutation in a Korean family and review of literature.
Not available
S-EPMC7549548 | biostudies-literature
UnknownTranscriptome profiling of Fraxinus excelsior genotypes infested by emerald ash borer.
Not available
S-EPMC10556020 | biostudies-literature
TranscriptomicsDNA methylation data from non-immortalized lymphocyte samples from participants of the AGES Reykjavik Study
Genome-wide DNA methylation was studied to identify regions with extreme inter-individual variability, half of which show stability within-person, and some of which show covariation with body mass index consistently and are located in or near genes previously implicated in regulating body weight or ...
ORGANISM(S): Homo sapiens 
2010-09-14 | E-GEOD-23858 | biostudies-arrayexpress
UnknownMusculoskeletal Education in Medical Schools: a Survey in California and Review of Literature.
Not available
S-EPMC8368391 | biostudies-literature
TranscriptomicsDNA methylation in postmortem brain samples from autism cases and controls
We used the Illumina 450KMethylation BeadChip to measure DNA methylation at 485,512 loci across the genome for 40 postmortem brain samples. The purpose of our study was to identify differentially methylated regions (DMRs) associated with autism. Samples included 16 temporal cortex brain tissue sampl...
ORGANISM(S): Homo sapiens 
2013-12-12 | E-GEOD-53162 | biostudies-arrayexpress
UnknownIdentification of a novel mutation in the FGF10 gene in a Chinese family with obvious congenital lacrimal duct dysplasia in lacrimo-auriculo-dento-digital syndrome.
Not available
S-EPMC10089906 | biostudies-literature
UnknownLeft atrium decompression devices across the spectrum of ejection fraction in heart failure: an updated systematic review and meta-regression analysis.
Not available
S-EPMC10403397 | biostudies-literature
UnknownDedicator of cytokinesis 8 is disrupted in two patients with mental retardation and developmental disabilities.
Not available
S-EPMC2245991 | biostudies-literature
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