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ProteomicsOptimizing efficacy to safety ratio of glucocorticoids in rheumatoid arthritis models by leveraging PPARα agonism
Glucocorticoids remain essential therapies for immune- and inflammatory diseases such as rheumatoid arthritis (RA) but are notorious for their metabolic side effects. Given the anti-inflammatory and metabolically favorable actions of peroxisome-proliferator activated nuclear receptor (PPAR) agonists...
ORGANISM(S): Homo sapiens (Human) 
2026-09-17 | PXD084343 | Pride
Human Gw7647 Ppar Dexamethasone Glucocorticoid hormones Fibroblast-like synoviocytes 
UnknownHigh resolution HLA analysis reveals independent class I haplotypes and amino-acid motifs protective for multiple sclerosis.
Not available
S-EPMC6035897 | biostudies-literature
UnknownThe Liver Cirrhosis Network Cohort Study: Cirrhosis Definition, Study Population, and Endpoints.
Not available
S-EPMC11739427 | biostudies-literature
UnknownSARS-CoV-2 Viral Load in the Nasopharynx at Time of First Infection Among Unvaccinated Individuals: A Secondary Cross-Protocol Analysis of 4 Randomized Trials.
Not available
S-EPMC11117088 | biostudies-literature
UnknownVirus genomes reveal factors that spread and sustained the Ebola epidemic.
Not available
S-EPMC5712493 | biostudies-literature
UnknownPreventive effects of early immunosuppressive treatment on the development of interstitial lung disease in systemic sclerosis.
Not available
S-EPMC12695046 | biostudies-literature
UnknownGastroesophageal reflux disease is associated with a more severe interstitial lung disease in systemic sclerosis in the EUSTAR cohort.
Not available
S-EPMC12695048 | biostudies-literature
UnknownClinical and Demographic Factors Associated With COVID-19, Severe COVID-19, and SARS-CoV-2 Infection in Adults: A Secondary Cross-Protocol Analysis of 4 Randomized Clinical Trials.
Not available
S-EPMC10346130 | biostudies-literature
UnknownPhenotypes Determined by Cluster Analysis and Their Survival in the Prospective European Scleroderma Trials and Research Cohort of Patients With Systemic Sclerosis.
Not available
S-EPMC6771590 | biostudies-literature
UnknownEffects of icosapent ethyl according to baseline residual risk in patients with atherosclerotic cardiovascular disease: results from REDUCE-IT.
Not available
S-EPMC11873788 | biostudies-literature
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