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TranscriptomicsExpression data from lack of DNA topoisomerase I, DNA topoisomerase II and complete lack of both topoisomerases
Here we dissect the transcriptional response in S. cerevisiae cells lacking DNA topoisomerases. We use microarray technology coupled with a functional genomics approach and demonstrate intimate connections between topoisomerase dependency, promoter chromatin architecture and gene transcription. Our ...
ORGANISM(S): Saccharomyces cerevisiae 
2012-07-31 | E-GEOD-22809 | biostudies-arrayexpress
TranscriptomicsTranscriptomic profiling of boars with high and low skatole levels
Skatole is one of the compounds causing boar taint in meat of uncastrated male pigs. This study focuses on differences in gene expression of 50 Danish Landrace boars with high and low skatole levels. The animals were divided into 2 groups based on the skatole measurements, with animals having a skat...
ORGANISM(S): Sus scrofa 
2015-06-15 | E-GEOD-29974 | biostudies-arrayexpress
TranscriptomicsEarly pig response to experimental infection with Actinobacillus pleuropneomuniae
The objective of this study was to identify porcine genes which expression was affected by experimental infection with A. pleuropneumoniae within 24 hours after experimental challenge. Microarray experiments were conducted to reveal genes being significantly differentially expressed in infected vers...
ORGANISM(S): Sus scrofa 
2010-06-11 | E-GEOD-4577 | biostudies-arrayexpress
TranscriptomicsTranscriptomic analysis of porcine muscle Biceps femoris (BF) exposed to a single bout of endurance exercise
Acute physical exercise elicits changes in gene expression in skeletal muscles to promote metabolic changes and to repair exercise-induced muscle injuries. Here, we investigated the impact of a single bout of running exercise until exhaustion on global transcriptional profiles in porcine skeletal mu...
ORGANISM(S): Sus scrofa 
2012-07-12 | E-GEOD-30013 | biostudies-arrayexpress
TranscriptomicsTranscriptomic analysis of porcine muscle Longissimus dorsi (LD) exposed to a single bout of endurance exercise
Acute physical exercise elicits changes in gene expression in skeletal muscles to promote metabolic changes and to repair exercise-induced muscle injuries. Here, we investigated the impact of a single bout of running exercise until exhaustion on global transcriptional profiles in porcine skeletal mu...
ORGANISM(S): Sus scrofa 
2012-07-12 | E-GEOD-30014 | biostudies-arrayexpress
MetabolomicsThe metabolic background is a global player in Saccharomyces gene expression epistasis
The regulation of gene expression in response to nutrient availability is fundamental to the genotype-phenotype relationship. The metabolic-genetic make-up of the cell, as reflected in auxotrophy, is hence likely to be a determinant of gene expression. Here, we address the importance of the metaboli...
2016-12-16 | MTBLS168 | MetaboLights
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