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ProteomicsGlobal Landscape of Cell Envelope Protein Complexes in Escherichia coli
After extraction with mild non-denaturing detergents, we affinity-purified 785 endogenously-tagged CEPs and then identified stably-associated polypeptides by precision mass spectrometry. The resulting high-quality physical interaction network, comprising most (77%) of all targeted CEPs, revealed hu...
ORGANISM(S): Escherichia coli (strain K12 / W3110 / ATCC 27325 / DSM 5911) 
2017-11-30 | PXD006247 | Pride
Escherichia coli Multi-protein complexes Macromolecues Protein-protein interactions Cell envelope Cell envelope proteins Cell envelope protein complexes 
ProteomicsRedesigned peptide-based LDH5 inhibitors enter cancer cells efficiently and impair proliferation
Lactate dehydrogenase 5 (LDH5), an enzyme overexpressed in many cancers, is an attractive target for anticancer therapy. Recently, we successfully designed an LDH5 peptide inhibitor, cGmC9, by targeting protein-protein interactions required for LDH5 enzymatic activity. LDH5 is expressed in the cytos...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2025-05-06 | PXD029126 | Pride
Peptide inhibitors Lactate dehydrogenase 
UnknownPosttraumatic Stress Symptom Trajectories Among Children After Disaster Exposure: A Review.
Not available
S-EPMC5953201 | biostudies-literature
TranscriptomicsLineage relationship in human dendritic cells - cDNA arrays
The lineage relationships and fate of human blood and tissue dendritic cells (DC) has significance for a number of diseases including HIV where both blood and tissue DC may be infected. We used gene expression profiling of monocyte and DC sub-populations sorted directly from blood and skin and compa...
ORGANISM(S): Homo sapiens 
2011-12-01 | E-GEOD-32648 | biostudies-arrayexpress
UnknownUnderstanding Open Access Data Using Visuals: Integrating Prospective Studies of Children's Responses to Natural Disasters.
Not available
S-EPMC8291378 | biostudies-literature
TranscriptomicsLineage relationship in human dendritic cells
The lineage relationships and fate of human blood and tissue dendritic cells (DC) has significance for a number of diseases including HIV where both blood and tissue DC may be infected. We used gene expression profiling of monocyte and DC sub-populations sorted directly from blood and skin and compa...
ORGANISM(S): Homo sapiens 
2011-12-01 | E-GEOD-32400 | biostudies-arrayexpress
UnknownPhotoacoustic Computed Tomography of Breast Cancer in Response to Neoadjuvant Chemotherapy.
Not available
S-EPMC8025032 | biostudies-literature
UnknownIncidence of type 2 diabetes mellitus in men receiving steroid 5α-reductase inhibitors: population based cohort study.
Not available
S-EPMC6456811 | biostudies-literature
UnknownUtilizing post-imaging surveys to guide development of photoacoustic computed technology for breast imaging.
Not available
S-EPMC12862834 | biostudies-literature
TranscriptomicsAbundant Quantitative Trait Loci for CpG Methylation and Expression Across Human Brain Tissues
A fundamental challenge in the post-genome era is to understand and annotate the consequences of genetic variation, particularly within the context of human tissues. We describe a set of integrated experiments designed to investigate the effects of common genetic variability on DNA methylation, mRNA...
ORGANISM(S): Homo sapiens 
2010-04-20 | E-GEOD-15745 | biostudies-arrayexpress
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