Sort   by:  
 Page size 
ProteomicsHomeostatic sleep regulation by microglial TNFalpha - a phosphoproteome study
To explore the role of microglial TNFα in the control of sleep through phosphorylation. Specifically, to examine the involvement of microglial TNFα in the control of brain phosphorylation along the sleep-wake cycle and in the phosphorylation-based coding of sleep need.
ORGANISM(S): Mus musculus (Mouse) 
2022-11-07 | PXD030568 | Pride
Sleep Phosphorylation Microglia Tnfα 
ProteomicsRagG interactome analysis in human breast MDA-MB-231 cells
RagC was immunoprecipitated from human breast cancer MDA-MB-231 cells treated or not with the Arp2/3 complex inhibitor, CK666, and the RagC interactome was analyzed by mass-spectrometry.
ORGANISM(S): Homo sapiens (Human) 
2023-09-04 | PXD027100 | Pride
Ragc Breast cancer cells Mtor Lysosomes 
ProteomicsQuantitative proteomic analysis of proteins bound to rs452384-T or rs452384-C
This project focuses on the functional characterization of a risk variant (SNP) implicated in the predisposition to uveal melanoma, rs452384. We sought to determine whether some nuclear factors could bind with allele-specificity a DNA sequence centered around rs452384 to regulate gene expression. We...
ORGANISM(S): Homo sapiens (Human) 
2022-11-15 | PXD028954 | Pride
Dna-protein interaction Transcription factors Allele-specific binding Rs452384 
ProteomicsNeonGreen-POLQ knock-in in Human embryonic kidney 293 cells VS Human embryonic kidney 293 cells
Replication stress (RS) can lead to the formation of DNA double strand breaks (DSBs) and threatens genomic stability. Homologous recombination (HR) pathway is essential to prevent RS and repairs associated DSBs. Upon excessive RS or HR deficiency, DSBs can persist in mitosis, wherein DNA damage resp...
ORGANISM(S): Homo sapiens (Human) 
2023-09-18 | PXD029585 | Pride
Polθ binding partners in human cells 
Sort   by:  
 Page size