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ProteomicsProteomic analysis of skeletal muscle reveals estrogen as a key regulator of muscle signaling in women
Women’s aging is characterized by menopausal loss of ovarian function, which has been suggested as a contributing factor to aging-related muscle deterioration and predisposes to the metabolic dysfunctions. However, the underlying molecular mechanisms have remained unknown. To identify mechanisms, we...
ORGANISM(S): Homo sapiens (Human) 
2017-09-12 | PXD006446 | Pride
Human Estrogen Hdmse Aging Muscle Hormon replacement therapy 
ProteomicsAccumulation of acylcarnitines and mitochondrial dysfunction characterize the loss of neonatal myocardial regeneration capacity
Myocardial regeneration capacity declines during the first week after birth and is linked to the adaptation to oxidative metabolism. Utilizing this regenerative window, we characterized the metabolic changes in myocardial injury in 1-day-old regeneration-competent and 7-day-old regeneration-compromi...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2022-02-04 | MSV000088783 | MassIVE
ProteomicsIntegrative organelle-based functional proteomics in ARSACS-focus on bioenergetics and autophagy
Autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS) is an inherited neurodegenerative disease characterized by early-onset spasticity in the lower limbs, axonal-demyelinating sensorimotor peripheral neuropathy, and cerebellar ataxia. Our understanding of the genetic basis, protein fun...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-12-20 | MSV000088592 | MassIVE
UnknownMolecular puzzle of insulin: structural assembly pathways and their role in diabetes.
Not available
S-EPMC11882602 | biostudies-literature
UnknownProbiotic Bacteria Survival and Shelf Life of High Fibre Plant Snack - Model Study.
Not available
S-EPMC11410916 | biostudies-literature
UnknownGlobal analysis of S-nitrosylation sites in the wild type (APP) transgenic mouse brain-clues for synaptic pathology.
Not available
S-EPMC4159650 | biostudies-literature
UnknownCharacterization of human palladin, a microfilament-associated protein.
Not available
S-EPMC60155 | biostudies-literature
UnknownUSP14 is crucial for proteostasis regulation and α-synuclein degradation in human SH-SY5Y dopaminergic cells.
Not available
S-EPMC11795799 | biostudies-literature
UnknownDynamic Interaction of USP14 with the Chaperone HSC70 Mediates Crosstalk between the Proteasome, ER Signaling, and Autophagy.
Not available
S-EPMC6941875 | biostudies-literature
UnknownSimple 3D culture of dissociated kidney mesenchyme mimics nephron progenitor niche and facilitates nephrogenesis Wnt-independently.
Not available
S-EPMC6748995 | biostudies-literature
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