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ProteomicsMolecular signatures after challenge with Salmonella Typhi implicate host tryptophan metabolism in the pathogenesis of typhoid fever, part 2
Label free quantitation using DIA HDMSe of Salmonella infected and uninfected mouse caecum tissue
ORGANISM(S): Mus musculus (Mouse) 
2020-01-21 | PXD001954 | Pride
Salmonella typhi Hdmse Label free Mouse Caecum Tissue 
ProteomicsAnalysis of LDL-associated proteins using the method of digitized native protein mapping
The method of digitized native protein mapping, combining nondenaturing micro 2DE, grid gel-cutting and quantitative LC-MS/MS (in data-independent acquisition mode, or MSE), was improved by using a new MS/MS mode, ion mobility separation enhanced-MSE (HDMSE) and applied to analyze the area of human ...
ORGANISM(S): Homo sapiens (Human) 
2016-05-17 | PXD003720 | Pride
Grid gel-cutting Quantitative lc-hdmse Human plasma low-density lipoprotein Protein-protein interactions Nondenaturing micro 2de Digitized native protein mapping 
UnknownIntegration of Data-Dependent Acquisition (DDA) and Data-Independent High-Definition MSE (HDMSE) for the Comprehensive Profiling and Characterization of Multicomponents from Panax japonicus by UHPLC/IM-QTOF-MS.
Not available
S-EPMC6695638 | biostudies-literature
ProteomicsBovine Longissimus thoracis muscle HDMSE with differents ultimate pH
The purpose of this research was to investigate the causes and consequences of pHu variations in beef cattle. For that, were evaluated 176 Nellore beef cattle, and classified into two different pHu groups: High (≥6.0, N=17) and Normal (<5.8, N=159). Plasma concentrations of cortisol and adrenocortic...
ORGANISM(S): Bos indicus 
2018-07-11 | PXD009320 | Pride
Bovine Hdmse Ultimate ph Muscle 
ProteomicsLabel-free quantitative proteomic analysis of DNA methyltransferase mutants of the cyanobacterium Synechocystis sp. PCC 6803 – Analysis of the membrane-enriched fraction
Total protein and membrane-enriched fractions of Synechocystis sp. PCC 6803 wild type (WT) and mutant strains affected with inactivated DNA methyltransferase genes were analyzed by LC-HDMSE. The mutation of the DNA methyltransferase gene sll0729 encoding M.Ssp6803II initially led to a strong phenoty...
ORGANISM(S): Synechocystis sp. (strain PCC 6803 / Kazusa) 
2019-06-26 | PXD012698 | Pride
Dna methyltransferase Hdmse Label-free quantification Suppressor mutants Synechocystis sp. pcc 6803 
ProteomicsLabel-free quantitative proteomic analysis of DNA methyltransferase mutants of the cyanobacterium Synechocystis sp. PCC 6803 – Analysis of total protein extracts
Total protein and membrane-enriched fractions of Synechocystis sp. PCC 6803 wild type (WT) and mutant strains affected with inactivated DNA methyltransferase genes were analyzed by LC-HDMSE. The mutation of the DNA methyltransferase gene sll0729 encoding M.Ssp6803II initially led to a strong phenoty...
ORGANISM(S): Synechocystis sp. (strain PCC 6803 / Kazusa) 
2019-06-26 | PXD012751 | Pride
Dna methyltransferase Hdmse Label-free quantification Suppressor mutants Synechocystis sp. pcc 6803 
ProteomicsOptimization of SILAC in human embryonic stem cells
We present a fully defined culture system (adapted Essential8 (E8) medium in combination with vitronectin) for human embryonic stem cells (hESC) that can be used for Stable Isotopic Labeling of Amino aCids (SILAC) purposes. Although a complete incorporation of the labels was observed after 4 days in...
ORGANISM(S): Homo sapiens (Human) 
2016-07-15 | PXD002859 | Pride
Culture Silac Hesc 
ProteomicsPLASMA PROTEOMIC ANALYSIS OF RARE BMI-DISCORDANT MONOZYGOTIC TWIN PAIRS
The aim of the current study is to establish the effect of excess body wiehgt and liver fat on plasma proteomic profile without interference from genetic variation. Label-free proteomics (HDMSE) was performed on plasma samples of young healthy monozygotic twins who were discordant for BMI. the twins...
ORGANISM(S): Homo sapiens (Human) 
2019-02-01 | PXD010691 | Pride
Hdmse Plasma proteomics Monozygotic twins Label-free proteomics Acquired obesity Complement activation 
ProteomicsMemory-enhancing effects of Origanum majorana essential oil in an Alzheimer's amyloid beta1-42 rat model: a molecular and behavioral study
Origanum L. (Lamiaceae) is an important genus of medicinal and aromatic plants used in the traditional medicine since ancient times as culinary herbs and remedies. The effects of Origanum majorana-based aromatherapy was investigated in an Alzheimer's amyloid beta1-42 rat model. Protein extracts from...
ORGANISM(S): Rattus norvegicus (Rat) 
2020-09-29 | PXD021082 | Pride
Alzheimer disease Rat Amyloid beta1-42 Brain tissue Origanum majorana 
ProteomicsQuantitative proteomic analysis of the Toxoplasma gondii cytoskeleton and bioinformatic identification of highly antigenic proteins
The Toxoplasma gondii cytoskeleton is a highly organized structure essential for parasite motility, replication, and host cell invasion. To identify its components, a highly enriched fraction of tachyzoite cytoskeletons was obtained and quantitatively analyzed by mass spectrometry (LC/ESI/HDMSE). We...
ORGANISM(S): Eukaryota Toxoplasma gondii RH 
2025-08-04 | PXD063409 | Pride
Toxoplasma gondii Quantitative mass spectrometry Immunogenic peptides Cytoskeleton 
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