Sort   by:  
 Page size 
UnknownLipid-Associated Macrophages Control Metabolic Homeostasis in a Trem2-Dependent Manner.
Not available
S-EPMC7068689 | biostudies-literature
UnknownA phase 1/2 study of the oral FLT3 inhibitor pexidartinib in relapsed/refractory FLT3-ITD-mutant acute myeloid leukemia.
Not available
S-EPMC7189289 | biostudies-literature
TranscriptomicsDiverse routes to oral cancer differing in genome instability and risk for cervical node metastasis
Clinically evident oral lesions, oral epithelial dysplasia, precede development of oral squamous cell carcinomas (SCC) and are considered to transform to cancer by acquisition of genetic or epigenetic alterations. Here, we show that, +3q24-qter, -8pter-p23.1, +8q12-q24.2 and +20 are early events id...
ORGANISM(S): Homo sapiens 
2011-11-18 | E-GEOD-28407 | biostudies-arrayexpress
ProteomicsProteasome inhibitor-induced modulation reveals the spliceosome as a specific therapeutic vulnerability in multiple myeloma
Resistance to proteasome inhibitors (PIs) is a ubiquitous clinical concern in multiple myeloma. We proposed that signaling-level responses after PI would reveal new means to enhance efficacy. Unbiased phosphoproteomics after the PI carfilzomib surprisingly demonstrated the most prominent phosphory...
ORGANISM(S): Homo sapiens (Human) 
2020-02-21 | PXD012172 | Pride
Cancer Multiple myeloma Splice factor Spliceosome Lc-msms phosphoproteomics Proteasome inhibition Splicing Alternative splicing 
UnknownRepurposing tofacitinib as an anti-myeloma therapeutic to reverse growth-promoting effects of the bone marrow microenvironment.
Not available
S-EPMC6029548 | biostudies-literature
UnknownCNS myelination requires VAMP2/3-mediated membrane expansion in oligodendrocytes.
Not available
S-EPMC9508103 | biostudies-literature
UnknownCRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis.
Not available
S-EPMC10312804 | biostudies-literature
UnknownAllosteric HSP70 inhibitors perturb mitochondrial proteostasis and overcome proteasome inhibitor resistance in multiple myeloma.
Not available
S-EPMC9434701 | biostudies-literature
UnknownNCCN Guidelines Insights: Kidney Cancer, Version 1.2021.
Not available
S-EPMC10191771 | biostudies-literature
UnknownKidney Cancer, Version 3.2022, NCCN Clinical Practice Guidelines in Oncology.
Not available
S-EPMC10191161 | biostudies-literature
Sort   by:  
 Page size