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TranscriptomicsSingle cell transcriptional profiling of mouse molar and incisor tooth assembloids
Throughout the various stages of tooth development, reciprocal epithelial-mesenchymal interactions are the driving force, for instance crucially involved in the differentiation of mature enamel-forming ameloblasts and dentin-producing odontoblasts. Here we established mouse tooth ‘assembloids’, comp...
ORGANISM(S): Mus musculus 
2023-04-19 | E-MTAB-12544 | biostudies-arrayexpress
TranscriptomicsSingle-cell transcriptional profiling of young-adult and aging (middle-aged) mouse anterior pituitary in steady-state conditions and after transgenically inflicted local damage
Adult pituitary stem cells (SC) are mainly dormant, yet in the case of damage the resident SC compartment shows swift activation. More in particular, following diphtheria toxin (DT)-triggered endocrine cell-ablation injury in the GHCre/iDTR mouse model (expressing the Cre recombinase under control o...
ORGANISM(S): Mus musculus 
2021-06-15 | E-MTAB-10021 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse primary capillary PlGF-/- endothelial cells treated with 100 ng/ml PlGF for 6 hours
PlGF expression profile in primary capillary PlGF-/- endothelial cells treated with 100 ng/ml PlGF during 6 hours.
ORGANISM(S): Mus musculus 
2003-05-28 | E-MEXP-6 | biostudies-arrayexpress
TranscriptomicsCentrosome amplification is sufficient to promote spontaneous tumorigenesis in mammals
Centrosome amplification is a common feature of human tumors, but whether this is a cause or a consequence of human cancer remains unclear. Here, we report the creation of a mouse model in which centrosome number can be persistently increased in the absence of additional genetic defects. We show tha...
ORGANISM(S): Mus musculus 
2017-02-04 | E-MTAB-5043 | biostudies-arrayexpress
UnknownAfatinib beyond progression in patients with non-small-cell lung cancer following chemotherapy, erlotinib/gefitinib and afatinib: phase III randomized LUX-Lung 5 trial.
Not available
S-EPMC4769992 | biostudies-literature
UnknownAssociation of Chromosome 9p21 With Subsequent Coronary Heart Disease Events.
Not available
S-EPMC6625876 | biostudies-literature
TranscriptomicsSingle cell sequencing of 3 lung carcinomas
Single cell sequencing of 3 lung tumours. 3 malignant tumor parts were sequenced for each tumor
ORGANISM(S): Homo sapiens 
2018-08-18 | E-MTAB-6653 | biostudies-arrayexpress
TranscriptomicsSingle cell sequencing of lung carcinoma
Single cell sequencing of 5 dissected lung tumors.
ORGANISM(S): Homo sapiens 
2018-07-09 | E-MTAB-6149 | biostudies-arrayexpress
UnknownCognitive function over time in the Alzheimer's Disease Anti-inflammatory Prevention Trial (ADAPT): results of a randomized, controlled trial of naproxen and celecoxib.
Not available
S-EPMC2925195 | biostudies-literature
UnknownIdentification of a BRCA2-specific modifier locus at 6p24 related to breast cancer risk.
Not available
S-EPMC3609647 | biostudies-literature
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