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GenomicsTranscriptomic changes in primary human keratinocytes following exposure to lamotrigine, lamotrigine-N2-oxide, lamotrigine in combination with valproic acid or interferon-γ, and interferon-γ alone
Transcriptomic changes in primary human keratinocytes following exposure to lamotrigine, lamotrigine-N2-oxide, lamotrigine in combination with valproic acid or interferon-γ, and interferon-γ alone
PRJNA1435889 | ENA
TranscriptomicsTranscriptomic changes in primary human keratinocytes following exposure to lamotrigine, lamotrigine-N2-oxide, lamotrigine in combination with valproic acid or interferon-γ, and interferon-γ alone
Bulk RNA sequencing with differential expression analysis was used to examine transcriptional changes in keratinocytes after exposure to lamotrigine (LTG), its CYP-mediated metabolite LTG-N2-oxide, and co-incubated LTG with valproic acid (VPA). IFN-γ served as a positive control, as its effects on k...
ORGANISM(S): Homo sapiens 
2026-03-30 | GSE324594 | GEO
UnknownLamotrigine ethanol monosolvate.
Not available
S-EPMC5947486 | biostudies-literature
UnknownEthosuximide, valproic acid, and lamotrigine in childhood absence epilepsy.
Not available
S-EPMC2924476 | biostudies-literature
UnknownAre doses of lamotrigine or levetiracetam adjusted during pregnancy?
Not available
S-EPMC5839303 | biostudies-literature
TranscriptomicsMicroarray profiling of rats treated for 21 days with Lithium chloride (0.2% in chow), Lamotrigine (30 mg/kg), or appropriately matched vehicles
SD rats were dosed with gold mood stabilizer therapies, lithium or lamotrigine, at doses aimed at achieving therapeutically relevant drug exposures. Tissues were collected after 21 days of delivery to examine the impact of this treatment on gene expression in frontal cortex, hippocampus and striatum...
ORGANISM(S): Rattus norvegicus 
2015-03-16 | GSE66276 | GEO
UnknownCardiac morbidity and mortality associated with the use of lamotrigine.
Not available
S-EPMC9796304 | biostudies-literature
UnknownAttenuation of amygdala atrophy with lamotrigine in patients receiving corticosteroid therapy.
Not available
S-EPMC3161623 | biostudies-literature
UnknownThe effectiveness of antiepileptic drug treatment in glioma patients: lamotrigine versus lacosamide.
Not available
S-EPMC8367894 | biostudies-literature
UnknownLamotrigine induced priapism in children: case analysis and literature review.
Not available
S-EPMC9703579 | biostudies-literature
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