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ProteomicsLAMTOR1 interactome upon mutation of USP32
Ubiquitination is among the most prevalent post-translational modifications regulating a great number of cellular functions, and defects in such processes contribute to many diseases. Deubiquitinating enzymes (DUBs) are essential to control the precise outcome of ubiquitin signals. The ubiquitin-spe...
ORGANISM(S): Homo sapiens (Human) 
2023-01-16 | PXD035974 | Pride
Rpe1 Interactome Lamtor1 Usp32 
ProteomicsLAMTOR1 interactome upon knock out of USP32
Ubiquitination is among the most prevalent post-translational modifications regulating a great number of cellular functions, and defects in such processes contribute to many diseases. Deubiquitinating enzymes (DUBs) are essential to control the precise outcome of ubiquitin signals. The ubiquitin-spe...
ORGANISM(S): Homo sapiens (Human) 
2023-01-16 | PXD024940 | Pride
Q exactive hf Lfq Lamtor1 Ubiquitin Usp32 Lc-ms/ms 
TranscriptomicsEssential roles of Lamtor1 in CD4+ T cell-mediated autoimmunity
Lamtor1 is a protein that is required for amino acid sensing and activation of mechanistic target of rapamycin complex 1 (mTORC1) at lysosomes. The critical role of Lamtor1 in macrophage polarization has been clarified recently. However, the role of Lamtor1 in adaptive immune system has not been inv...
ORGANISM(S): Mus musculus 
2017-01-16 | GSE92946 | GEO
UnknownLAMTOR1 regulates dendritic lysosomal positioning in hippocampal neurons through TRPML1 inhibition.
Not available
S-EPMC11621854 | biostudies-literature
GenomicsMus musculus
Essential roles of Lamtor1 in CD4+ T cell-mediated autoimmunity
PRJNA359121 | ENA
UnknownPolarization of M2 macrophages requires Lamtor1 that integrates cytokine and amino-acid signals.
Not available
S-EPMC5064021 | biostudies-literature
UnknownPlatelet-Derived Microvesicles Promote VSMC Dedifferentiation After Intimal Injury via Src/Lamtor1/mTORC1 Signaling.
Not available
S-EPMC8481604 | biostudies-literature
UnknownLAMTOR1 degrades MHC-II via the endocytic in hepatocellular carcinoma.
Not available
S-EPMC9890926 | biostudies-literature
UnknownLAMTOR1 decreased exosomal PD-L1 to enhance immunotherapy efficacy in non-small cell lung cancer.
Not available
S-EPMC11367890 | biostudies-literature
UnknownLAMTOR1 inhibition of TRPML1-dependent lysosomal calcium release regulates dendritic lysosome trafficking and hippocampal neuronal function.
Not available
S-EPMC8886530 | biostudies-literature
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