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TranscriptomicsCCR8 expression defines tissue-resident memory T cells in human skin
Human skin harbors two major T cell compartments of equal size that are distinguished by expression of the chemokine receptor CCR8. In vitro studies have demonstrated that CCR8 expression is under strict control of T cell antigen receptor (TCR)-engagement and the skin tissue microenvironment. We her...
ORGANISM(S): Homo sapiens 
2017-12-11 | E-MTAB-6370 | biostudies-arrayexpress
UnknownDepletion of exhausted alloreactive T cells enables targeting of stem-like memory T cells to generate tumor-specific immunity.
Not available
S-EPMC10184646 | biostudies-literature
TranscriptomicsRNA-seq of effector (CD43+) CD8+ T cells, CD45+ hematopoietic cells and CD45- tumor/stromal cells from mice bearing bilateral AT-3 tumors following radio-immunotherapy of which one tumor was irradiated
Radiotherapy (RT) destroys tumor cells, which may lead to release of antigens and immune-activating signals. In this way, RT may act as an in situ vaccine and kick-start a T-cell response against the tumor. Immunotherapy enhances tumor-specific T-cell responses. Combination of radiotherapy and immun...
ORGANISM(S): Mus musculus 
2019-02-12 | E-MTAB-6914 | biostudies-arrayexpress
GenomicsAutophagic adaptation to oxidative stress alters peritoneal residential macrophage survival and ovarian cancer metastasis [macrophages]
Autophagic adaptation to oxidative stress alters peritoneal residential macrophage survival and ovarian cancer metastasis [macrophages]
PRJNA662367 | ENA
UnknownDevelopment of pharmacological immunoregulatory anti-cancer therapeutics: current mechanistic studies and clinical opportunities.
Not available
S-EPMC11109181 | biostudies-literature
TranscriptomicsExpression data of wild type and C-DGCR8 KO cones at different timepoints [RNA-seq]
We have analyzed gene expression in cone photoreceptors isolated from wild type and C-DGCR8 (DiGeorge Syndrome Critical Region Gene 8) KO mice at five different time points to get a mechanistic inside into the altered molecular pathways after microRNAs depletion. Cones were isolated by FACS from wil...
ORGANISM(S): Mus musculus 
2014-06-20 | E-GEOD-58498 | biostudies-arrayexpress
TranscriptomicsMiRNAs 182 and 183 are necessary to maintain adult cone photoreceptor outer segments and visual function
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2014-06-20 | E-GEOD-58501 | biostudies-arrayexpress
UnknownProteomic identification of immunoproteasome accumulation in formalin-fixed rodent spinal cords with experimental autoimmune encephalomyelitis.
Not available
S-EPMC3312875 | biostudies-literature
GenomicsChIP-seq defined genome-wide map of TGFbeta/SMAD4 targets: implications with clinical outcome of ovarian cancer patients
Deregulation of the transforming growth factor-? (TGF?) signaling pathway in epithelial ovarian cancer has been reported, but the precise mechanism underlying disrupted TGF? signaling in the disease remains unclear. We performed chromatin immunoprecipitation followed by sequencing (ChIP-seq) to inve...
ORGANISM(S): Homo sapiens 
2011-06-30 | E-GEOD-27526 | biostudies-arrayexpress
UnknownPlasma proteins associated with cardiovascular death in patients with chronic coronary heart disease: A retrospective study.
Not available
S-EPMC7817029 | biostudies-literature
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