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TranscriptomicsTranscription profiling by array of human stromal cells cultured with or without 3D BPH-1 prostate epithelial cells
BPH-1 prostate epithelial cells when cultured in Matrigel form 3D acini which closely recapitulate the tissue architecture of the prostate. The presence of primary stroma increases epithelial adhesions and causes changes in morphology. To identify the stromal signals which control actin/cadherin dy...
ORGANISM(S): Homo sapiens 
2010-06-09 | E-MEXP-2657 | biostudies-arrayexpress
TranscriptomicsNascent mRNA profiling of LPS-stimulated mouse macrophages
To identify transcriptionally regulated genes in primary mouse macrophages stimulated with LPS with high sensitivity, we isolated nascent RNA following metabolic labelling with 4-thiouridine during the last 35 min before cell harvest, as recently described (Dolken et al. 2008 RNA 14:1959-72). Microa...
ORGANISM(S): Mus musculus 
2010-05-07 | E-GEOD-20674 | biostudies-arrayexpress
UnknownImpact of COVID-19 pandemic-induced surgical restrictions on operational performance: a case study at the University Hospital of Ulm.
Not available
S-EPMC11599351 | biostudies-literature
TranscriptomicsTranscription profiling of Physcomitrella patens Gransden strain
Transcription profiling of Physcomitrella patens Gransden strain
ORGANISM(S): Physcomitrella patens 
2014-05-07 | E-MTAB-917 | biostudies-arrayexpress
UnknownMesalamine modulates intercellular adhesion through inhibition of p-21 activated kinase-1.
Not available
S-EPMC3557386 | biostudies-literature
TranscriptomicsTranscription profiling of Physcomitrella patens gametophores under cold stress
Temperature reduction is a common environmental stress for plants. Land plants need to cope with cold stress on the basis of complex transcriptional and metabolic changes. The transcriptional responses and signaling networks that contribute to cold acclimation of seed plants have been analyzed previ...
ORGANISM(S): Physcomitrella patens 
2014-11-27 | E-MTAB-2165 | biostudies-arrayexpress
TranscriptomicsThe unfolded protein response in fission yeast modulates stability of select mRNAs to maintain protein homeostasis
Homeostatic control mechanisms are essentil to life. One such mechanism, the unfolded protein response (UPR) operates in all eukarytic cells to adjust protein folding capacity of the endoplasmic reticulum (ER) according to need. UPR induction in all eurkarytic cells to date involves Ire1 (kinase/end...
ORGANISM(S): Schizosaccharomyces pombe 
2012-11-21 | E-GEOD-40298 | biostudies-arrayexpress
TranscriptomicsRNA-seq of islet, FACS- sorted CD45+Ly6C-CD11B+CD11C+F4/80+ cells from C57bl6/J male mice that were treated with low dose streptozotocin (STZ) or acetate buffer
The experiment was designed to obtain a broader unbiased view of the changes in islet macrophages following low dose STZ challenge. Mice were purchased from Jackson Laboratory (Bar Harbor, ME). 16-20-week-old C57BL/6J males were given 30 mg/kg STZ or acetate buffer (control) i.p. (intraperitoneal ...
ORGANISM(S): Mus musculus 
2019-11-01 | E-MTAB-7234 | biostudies-arrayexpress
UnknownLocal Phototherapy Synergizes with Immunoadjuvant for Treatment of Pancreatic Cancer through Induced Immunogenic Tumor Vaccine.
Not available
S-EPMC6214772 | biostudies-literature
TranscriptomicsTranscription profiling of mouse lung from a strain overexpressing IL-10 under control of the macrophage-specific CD68 promoter (macIL-10tg mice) after Mycobacterium tuberculosis infection
The cytokine IL-10 deactivates macrophages and has been shown to impair resistance to mycobacterial infection. We have infected transgenic mice overexpressing IL-10 under control of the macrophage-specific CD68 promoter (macIL-10tg mice) with Mycobacterium tuberculosis by aerosol and found increased...
ORGANISM(S): Mus musculus 
2009-01-17 | E-GEOD-14316 | biostudies-arrayexpress
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