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TranscriptomicsGlobal profiling of gene expression in the ΔdigR and ΔsgmT mutant of Myxococcus xanthus
In Myxococcus xanthus 55% of the more than 250 two-component signal transduction systems (TCS) genes are orphan. We hypothesized that the histidine kinase SgmT and the response regulator DigR, which comprises a DNA binding domain of the HTH_Xer type, function together to regulate gene expression. We...
ORGANISM(S): Myxococcus xanthus 
2012-05-17 | E-GEOD-34408 | biostudies-arrayexpress
ProteomicsDifferential Proteome Analysis of Human Neuroblastoma Xenograft Primary Tumors and Matched Spontaneous Distant Metastases
Metastasis formation is the major cause for cancer-related deaths and the underlying mechanisms remain poorly understood. In this study we describe spontaneous metastasis xenograft mouse models of human neuroblastoma used for unbiased identification of metastasis-related proteins by applying an infr...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2018-09-24 | PXD009744 | Pride
Bioluminescence imaging Proteome analysis Spontaneous metastasis Infrared laser ablation 
TranscriptomicsL-Glutamine metabolism and its regulation in C. glutamicum
Corynebacterium glutamicum, a gram-positive soil bacterium used for the industrial production of amino acids such as L-glutamate and L-lysine, is able to use a number of different nitrogen sources, such as ammonium, urea, or creatinine. In this communication, we show that L-glutamine serves as an ex...
ORGANISM(S): Corynebacterium glutamicum ATCC 13032 
2010-10-05 | E-GEOD-19779 | biostudies-arrayexpress
UnknownExpression, purification, and inhibition profile of dihydrofolate reductase from the filarial nematode Wuchereria bancrofti.
Not available
S-EPMC5963757 | biostudies-literature
TranscriptomicsDeciphering the transcriptional adaptation of Corynebacterium glutamicum in transition from aerobiosis via microaerobiosis to anaerobiosis via RNA-seq
To investigate the adaptation of Corynebacterium glutamicum to altering oxygen availabilities, we conceived a triple-phase fermentation process that describes a gradual reduction of dissolved oxygen depicting a shift from aerobiosis via microaerobiosis to anaerobiosis. The distinct process phases we...
ORGANISM(S): Corynebacterium glutamicum ATCC 13032 
2018-03-31 | E-MTAB-6602 | biostudies-arrayexpress
UnknownDe novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population.
Not available
S-EPMC7007577 | biostudies-literature
UnknownAssociations of common breast cancer susceptibility alleles with risk of breast cancer subtypes in BRCA1 and BRCA2 mutation carriers.
Not available
S-EPMC4406179 | biostudies-literature
UnknownIdentification of six new susceptibility loci for invasive epithelial ovarian cancer.
Not available
S-EPMC4445140 | biostudies-literature
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