Sort   by:  
 Page size 
ProteomicsCompetition-based, quantitative chemical proteomics in breast cancer cells identifies new target profiles for sulforaphane
Sulforaphane is a small molecule isothiocyanate which exhibits anticancer potential, yet its biological targets remain poorly understood. Here we employ a competition-based chemical proteomics strategy to profile sulforaphane’s targets and identify over 500 targets along with their relative affiniti...
ORGANISM(S): Homo sapiens (Human) 
2017-05-24 | PXD006279 | Pride
Sulforaphane  cancer  chemical proteomics 
ProteomicsSpsB is a target of SOS-response inhibitor OXF‑077 and regulates quinolone resistance emergence
Antimicrobial resistance (AMR) is a global health threat, urgently requiring novel compounds with new targets. One emerging strategy is the development of ‘antibiotic adjuvants’ that inhibit the mutagenic SOS response in bacteria, thus prolonging antibiotic efficacy. OXF‑077 is a potent SOS-response...
ORGANISM(S): Staphylococcus aureus 
2026-05-21 | PXD071059 | Pride
Sort   by:  
 Page size