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TranscriptomicsMulti-region copy-number analysis
Intra-tumour heterogeneity (ITH) foster tumour adaptation and hamper the efficiency of personalised medicine approaches. We investigated the extent of ITH within individual clear cell renal cell carcinomas (ccRCC) by multi-region sampling and copy number analysis. We analyzed 63 tumour regions and 8...
ORGANISM(S): Homo sapiens 
2013-06-04 | E-GEOD-47077 | biostudies-arrayexpress
UnknownLonger Follow-Up Confirms Relapse-Free Survival Benefit With Adjuvant Dabrafenib Plus Trametinib in Patients With Resected BRAF V600-Mutant Stage III Melanoma.
Not available
S-EPMC6286159 | biostudies-literature
GenomicsWhole genome sequencing and whole exome sequencing of mucosal melanoma
We conducted whole genome sequencing of 5 mucosal melanomas and their matched DNA from blood. We conducted whole exome sequencing of a further 5 mucosal melanomas and their matched DNA from blood.
EGAS00001000474 | EGA
Genomicsena-DATASET-PICR-28-07-2014-16:35:04:391-518 - samples
NGS of 10 mucosal melanomas: Whole genome sequencing of 5 mucosal melanomas and matched normal DNA Whole exome sequencing of 5 mucosal melanomas and matched normal DNA
EGAD00001000945 | EGA
Genomicsena-DATASET-CRUK-LRI-04-02-2014-11:46:00:265-3 - samples
Paired end Illumina sequencing of whole exomes of multiple tumour regions.
EGAD00001000734 | EGA
GenomicsGenomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing
We applied multi-region exome sequencing to 10 clear cell renal carcinomas to resolve the genetic architecture, intra tumour heterogeneity and evolutionary histories of these tumours.
EGAS00001000667 | EGA
GenomicsTRACERx renal DAC
Data Access Committee EGAC00001001907
EGAC00001001907 | EGA
Genomicsena-DATASET-CRUK-LRI-05-08-2014-14:10:54:243-46 - samples
Van Hippel-Lindau syndrome multi-region exome sequencing of two patients
EGAD00001000973 | EGA
GenomicsVon Hippel-Lindau syndrome multi-region exome sequencing project from two patients undertaken at Cancer Research UK's London Research Institute
Multi-region whole exome sequencing of tumours from patients with Von Hippel-Lindau syndrome reveals convergence of mutayional events upon the PI3L-AKT-mTOR signalling pathway.
EGAS00001000907 | EGA
UnknownFixed dosing versus weight-based dosing of HIV-1 prophylactic monoclonal antibodies in adults: a post-hoc, cross-protocol pharmacokinetics modelling study.
Not available
S-EPMC12205768 | biostudies-literature
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