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ProteomicsA proteomic approach to identify alterations in the SUMO network during controlled mechanical ventilation in rat diaphragm muscle
SUMOylation is a key post-translational modification that regulates crucial cellular functions and pathological processes. It has emerged as a fundamental route that may drive different steps of human diseases. Indeed, alteration in expression or activity of one of the different SUMO pathway compone...
ORGANISM(S): Rattus norvegicus (Rat) 
2017-04-05 | PXD006085 | Pride
Mechanical ventilation Sumo Sumo biomarkers Diaphragm Skeletal muscle 
TranscriptomicsFunctional tissue specific MSC in lung-transplanted patients with and without bronchiolitis obliterans syndrome (BOS) - a potential source for cell-therapy?
Background: Mesenchymal stromal cells (MSC) have been proposed as a future cell based therapy for lung diseases like bronchiolitis obliterans syndrome (BOS). Theoretically, it might be beneficial to use lung resident MSC already adapted to the pulmonary environment. We therefore aimed to compare lun...
ORGANISM(S): Homo sapiens 
2016-08-01 | E-GEOD-74163 | biostudies-arrayexpress
TranscriptomicsWhite adipose tissue browning in the R6/2 mouse model of Huntington's disease
We investigated gene expression signatures in subcutaneous inguinal adipose tissue obtained from wild type and R6/2 mice with the aim to identify gene expression changes and signalling pathway alterations in adipose tissue relevant to HD. Gene expression was assessed using Affymetrix GeneChip® Mous...
ORGANISM(S): Mus musculus 
2016-07-28 | E-GEOD-79711 | biostudies-arrayexpress
UnknownContinuous vs Intermittent β-Lactam Antibiotic Infusions in Critically Ill Patients With Sepsis: The BLING III Randomized Clinical Trial.
Not available
S-EPMC11170452 | biostudies-literature
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