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MetabolomicsMetabolomic analysis reveals a differential adaptation process of the larval stages of Anisakis simplex to the host environment

Anisakis simplex are parasitic nematodes that cause anisakiasis. The possibility of infection with this parasite is through consumption of raw or undercooked fish products. A. simplex infections are often misdiagnosed, especially in subclinical cases that do not present with typ...

2023-07-08 | MTBLS6458 | MetaboLights
MetabolomicsGregarines impact consumption and development but not glucosinolate metabolism in the mustard leaf beetle

Gregarines are usually classified as parasites, but recent studies suggest that they should be viewed on a parasitism-mutualism spectrum and may even be seen as part of the gut microbiota of host insects. As such, they may also impact the consumption of their hosts and/or be involved in the diges...

2025-07-10 | MTBLS9816 | MetaboLights
MetabolomicsCascading effects of root microbial symbiosis on the development and metabolome of the insect herbivore Manduca sexta L

Root mutualistic microbes can modulate the production of plant secondary metabolites affecting plant–herbivore interactions. Still, the main mechanisms underlying the impact of root mutualists on herbivore performance remain ambiguous. In particular, little is known about how changes in the plant...

2023-09-12 | MTBLS2700 | MetaboLights
MetabolomicsContribution of fungal microbiome to intestinal physiology, early-life immune development and mucosal inflammation in mice
The gut microbiome consists of a multi-kingdom microbial community. Whilst the role of bacteria as causal contributors governing host physiological development is well established, the role of fungi remains to be determined. Here, we use germ-free mice colonized with defined species of bacteria, fun...
2022-01-14 | MTBLS1679 | MetaboLights
ProteomicsProteomic characterisation of Caenorhabditis elegans larval development
The nematode Caenorhabditis elegans (C. elegans) is often used as a model organism to study cell and developmental biology. Quantitative mass spectrometry has only recently been performed in C. elegans and, so far, most studies have been done on adult worm samples. Here we use quantitative mass spec...
ORGANISM(S): Caenorhabditis elegans 
2017-12-04 | PXD006676 | Pride
Caenorhabditis elegans Lc-ms Larvae Development 
MetabolomicsBiotransformation causes the sex-specific regulation of polychlorinated biphenyls during metamorphosis of silkworm (Bombyx mori) and their effect on the silkworm development

The decline in insect populations is indisputable. Currently, the effects of persistent organic pollutants on insect populations have not been sufficiently investigated. Maternal transfer of pollutants is considered to be an inherently correct reason for sex differences in pollutant le...

2025-09-09 | MTBLS12906 | MetaboLights
TranscriptomicsGene expression profiling of Schistosoma mansoni larval development using serial analysis of gene expression (SAGE)
Biomphalaria glabrata infection by the Schistosoma mansoni free-swimming miracidium and its subsequent development to the parasitic sporocyst stage is critical to establishment of viable infections and triggers a variety of physiological, biochemical and molecular changes. Here, we describe a genom...
ORGANISM(S): Schistosoma mansoni 
2009-03-09 | E-GEOD-9722 | biostudies-arrayexpress
TranscriptomicsTranscriptomic Analysis of Differentially Expressed Genes during Larval Development of Rapana Venosa by Digital Gene Expression Profiling
In present study, digital gene expression (DGE) profiling was performed to obtain a general picture of the transcriptomic implicated in the early development of R. venosa. Eighteen DGE libraries at six developmental stages of R. venosa were constructed, sequenced by IIIumina HiSeq 2500 platform. RNA...
ORGANISM(S): Rapana venosa 
2016-07-22 | E-GEOD-70548 | biostudies-arrayexpress
TranscriptomicsUse of an activated beta-catenin to identify Wnt/beta-catenin pathway target genes in C. elegans, including a subset of collagen genes expressed in late larval development
The Wnt signaling pathway plays a fundamental role during the development of metazoans, where it functions in the regulation of diverse processes including cell fate specification, cell migration, and stem cell renewal. Activation of the beta-catenin dependent or canonical Wnt signaling pathway upr...
ORGANISM(S): Caenorhabditis elegans 
2014-05-13 | E-GEOD-51502 | biostudies-arrayexpress
GenomicsTranscriptomic study of the Drosophila midgut during larval development
Transcriptomic study of the Drosophila midgut during larval development
PRJNA1192207 | ENA
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