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UnknownAssociation of metabolic syndrome and its components with arterial stiffness in Caucasian subjects of the MARK study: a cross-sectional trial.
Not available
S-EPMC5078926 | biostudies-literature
GenomicsChIP-Seq reveals regulation of the heterochromatic mark, H3K9me3, in NAc following repeated cocaine administration
Repeated administration of the psychostimulant cocaine has been shown to produce persistent alterations in genome-wide transcriptional regulatory networks, chromatin remodeling activity and, ultimately, gene expression profiles in the brain’s reward circuitry. Virtually all previous investigations h...
ORGANISM(S): Mus musculus 
2011-01-18 | E-GEOD-24850 | biostudies-arrayexpress
UnknownA body shape index and vascular structure and function in Spanish adults (MARK study): A cross-sectional study.
Not available
S-EPMC6392544 | biostudies-literature
ProteomicsIsonicotinylation is Isonicotinylation is a histone mark induced by the anti-tuberculosis first-line drug isoniazida histone mark induced by the anti-tuberculosis first-line drug isoniazid
Isoniazid (INH) is the first-line anti-tuberculosis drug used for nearly seventy years. Metabolites of INH showed hepatotoxicity in human and tumorigenicity in rodents. However, mechanism underlying the side effects of INH is elusive. Histone acylation is known to be modulated by intracellular metab...
ORGANISM(S): Homo sapiens (Human) 
2021-08-20 | PXD025490 | Pride
Histone isonicotinyltransferases Histone deisonicotinylases Gene transcription Histone isonicotinylation Chromatin structure 
ProteomicsChromatin proteomics reveals novel combinatorial histone modification signatures that mark distinct subpopulations of macrophage enhancers
The integrated activity of cis-regulatory elements fine-tunes transcriptional programs of mammalian cells by recruiting cell type–specific as well as ubiquitous transcription factors (TFs). Despite their key role in modulating transcription, enhancers are still poorly characterized at the molecular ...
ORGANISM(S): Mus musculus (Mouse) 
2017-10-09 | PXD007582 | Pride
Lc-msms Enhancers Histone ptms 
UnknownDecadal-scale onset and termination of Antarctic ice-mass loss during the last deglaciation.
Not available
S-EPMC8602255 | biostudies-literature
UnknownDisappearance of the last tropical glaciers in the Western Pacific Warm Pool (Papua, Indonesia) appears imminent.
Not available
S-EPMC6936586 | biostudies-literature
ProteomicsTrypanosoma brucei histones are heavily modified with combinatorial post-translational modifications and mark Pol II transcription start regions with hyperacetylated H2A.
Trypanosomes diverged from the main eukaryotic lineage about 600 million years ago, and display some unusual genomic and epigenetic properties that provide valuable insight into the early processes employed by eukaryotic ancestors to regulate chromatin-mediated functions. We sequenced Trypanosoma br...
ORGANISM(S): Trypanosoma brucei 
2022-08-21 | PXD024574 | Pride
Combinatorial histone post-translational modification Transcription Epigenetics Trypanosoma brucei Histone hyperacetylation 
GenomicsA Novel HDAC Complex in the Control of Transcription and Genome Stability
The acetylation state of histones, controlled by histone acetyltransferases and deacetylases, profoundly affects DNA transcription and repair by modulating chromatin accessibility to the cellular machinery. The Schizosaccharomyces pombe HDAC Clr6 (human HDAC1) binds to different sets of proteins tha...
ORGANISM(S): Schizosaccharomyces pombe 
2014-07-10 | E-GEOD-57040 | biostudies-arrayexpress
UnknownFactors associated with calendar literacy and last menstrual period (LMP) recall: a prospective programmatic implication to maternal health in Bangladesh.
Not available
S-EPMC7737077 | biostudies-literature
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