BACKGROUND: In all living organisms, DNA replication is exquisitely regulated in a wide range of growth conditions to achieve timely and accurate genome duplication prior to cell division. Failures in this regulation cause DNA damage with potentially disastrous consequences ...
The Retro-MATISSE study (Molecular Analysis of Thrombus for Ischemic Stroke prognosiS and Etiology) aimed to characterize the metabolome of 334 thrombi <...
Our objective is to identify the metabolites associated with stability of carotid atheromatous plaques compared to vulnerable plaques, through a metabolomic approach. Eighty consecutive patients with carotid artery stenosis (CAS) who underwent carotid endarterectomy (CEA) according to current guidel...
We have used a lipoprotein-deficient mutant Streptococcus pneumoniae strain, delta lgt, to investigate the role of lipoproteins during inflammatory responses to live S. pneumoniae.
The amounts of eIF4G and eIF4B were decreased in the vemurafenib-treated sensitive A375 cell line. To find mechanisms behind this decrease, we sought to identify the genes whose expression changes after vemurafenib treatment in A375 cells as compared to Mel624 cells by using microarrays.
Trisomy 21 (T21) is the most frequent genetic cause of cognitive impairment. To assess the perturbations of gene expression in T21, and to eliminate the noise of the genomic variability, we studied the transcriptome of fetal fibroblasts from a pair of monozygotic twins discordant for T21. Here we sh...
Trisomy 21 (T21) is the most frequent genetic cause of cognitive impairment. To assess the perturbations of gene expression in T21, and to eliminate the noise of the genomic variability, we studied the transcriptome of fetal fibroblasts from a pair of monozygotic twins discordant for T21. Here we sh...
