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ProteomicsExploring the molecular mechanisms behind the potentiation of chemotherapy effects by durvalumab in lung adenocarcinoma cell lines
Immune checkpoint inhibitors are increasingly used in combination with chemotherapy for treatment of non-small cell lung cancer, yet the success of combination therapies is relatively limited. Thus, more detailed insight regarding the tumour molecular markers that may affect the responsiveness of pa...
ORGANISM(S): Homo sapiens (Human) 
2023-05-12 | PXD040761 | Pride
Chemosensitivity Proteomics Resistance Lung adenocarcinoma Pemetrexed Durvalumab Cisplatin 
ProteomicsProteome changes associated with effect of high-dose single-fractionation radiation on lung adenocarcinoma cell lines
Lung cancer is a leading cause of cancer-related mortality globally, with non-small cell lung cancer (NSCLC) representing 85% of cases. Advances in treatment modalities, including the emergence of antibody-drug conjugates and stereotactic radiation therapy, have improved outcomes. However, the possi...
ORGANISM(S): Homo sapiens (Human) 
2025-07-06 | PXD057576 | Pride
Proteomics Ephrin type-a receptor 2 High-dose radiation Lung adenocarcinoma 3d cell culture 
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