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TranscriptomicsTranscription profiling of human neuroblastoma cell lines using a dene-resolution analysis method of DNA copy number variation using oligonucleotide expression microarrays
We present a novel method of using commercial oligonucleotide expression microarrays for aCGH, enabling DNA copy number measurements and expression profiles to be combined using the same platform. This method yields aCGH data from genomic DNA without complexity reduction at a median resolution of ap...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7364 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis of high Arctic soil bacterial response to hydrocarbon pollution and bioremediation: 16S rRNA
High Arctic soils have low nutrient availability, low moisture content and very low temperatures and, as such, they pose a particular problem in terms of hydrocarbon bioremediation. An in-depth knowledge of the microbiology involved in this process is likely to be crucial to understand and optimize ...
ORGANISM(S): Bacteria 
2010-06-19 | E-GEOD-17532 | biostudies-arrayexpress
TranscriptomicsDiet rapidly and reproducibly alters the human gut microbiome
Long-term dietary intake influences the structure and activity of the trillions of microorganisms residing in the human gut, but it remains unclear how rapidly and reproducibly the human gut microbiome responds to short-term macronutrient change. Here we show that the short-term consumption of diets...
ORGANISM(S): human gut metagenome 
2013-12-05 | E-GEOD-46761 | biostudies-arrayexpress
UnknownDelivery of an enzyme-IGFII fusion protein to the mouse brain is therapeutic for mucopolysaccharidosis type IIIB.
Not available
S-EPMC4205671 | biostudies-literature
UnknownProtein crystal structure obtained at 2.9 A resolution from injecting bacterial cells into an X-ray free-electron laser beam.
Not available
S-EPMC4156696 | biostudies-literature
UnknownHigh-speed fixed-target serial virus crystallography.
Not available
S-EPMC5588887 | biostudies-literature
UnknownDonepezil delays progression to AD in MCI subjects with depressive symptoms.
Not available
S-EPMC2697965 | biostudies-literature
UnknownResults of the two incidence screenings in the National Lung Screening Trial.
Not available
S-EPMC4307922 | biostudies-literature
GenomicsWhole Exome Sequencing of Chronic Lymphocytic Leukemia

The somatic genetic basis of chronic lymphocytic leukemia (CLL), a common and clinically heterogenous adult leukemia, remains poorly understood. Massively parallel sequencing technology now provides a method for systematic discovery of genetic alterations that underlie disease, and for uncovering...

phs000435.v1.p1 | EGA
TranscriptomicsCells Comprising the Prostate Cancer Microenvironment Lack Recurrent Clonal Somatic Genomic Aberrations
Prostate cancer-associated stroma (CAS) plays an active role in malignant transformation, tumor progression, and metastasis. Molecular analyses of CAS have demonstrated significant changes in gene expression; however, conflicting evidence exists on whether genomic alterations in benign cells compris...
ORGANISM(S): Homo sapiens 
2016-02-12 | E-GEOD-76456 | biostudies-arrayexpress
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