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TranscriptomicsSequencing of murine corticotrophs from male and female POMC-GFP mice.
Stress-related illness represents a major burden on health and society. Understanding the molecular mechanisms underlying stress responses is an important step to understand these diseases, and design treatments. Sexual dimorphism in stress responses have been extensively reported, with depression a...
ORGANISM(S): Mus musculus 
2023-05-03 | E-MTAB-12885 | biostudies-arrayexpress
TranscriptomicsSequencing of murine corticotrophs from male POMC-GFP mice subjected to chronic restraint stress
Stress-related illness represents a major burden on health and society. Understanding the molecular mechanisms underlying stress responses is an important step to understanding these diseases and designing treatments. Corticotrophs of the anterior pituitary play a central role in the generation of h...
ORGANISM(S): Mus musculus 
2024-10-30 | E-MTAB-13648 | biostudies-arrayexpress
ProteomicsCryo-EM structure of the extracellular domain of murine Thrombopoietin Receptor in complex with Thrombopoietin.
The haematopoietic cytokine thrombopoietin (Tpo) is the primary regulator of megakaryocyte and platelet numbers and is required for maintenance of the haematopoetic stem cell compartment. Tpo is a heavily glycosylated, hepatocyte-derived cytokine which functions by binding to its receptor (TpoR) on ...
ORGANISM(S): Homo sapiens (Human) 
2024-01-09 | PXD046926 | Pride
Glycosylation Tpor Cryo-em 
UnknownThe impact of low-mode symmetry on inertial fusion energy output in the burning plasma state.
Not available
S-EPMC10998902 | biostudies-literature
GenomicsICGC Benchmark 1 (CLL) - samples
Raw fastq files from WGS sequencing of CLL and matching blood normal for the ICGC Techval Benchmark1 study. Sequence data was provided to multiple centers for independent analysis and comparison.
EGAD00001001858 | EGA
GenomicsICGC Benchmark 2 (Medulloblastoma) - samples
Raw fastq files for sequence data generated at 5 sequencing centers from a Medulloblastoma sample and matching blood normal control.
EGAD00001001859 | EGA
GenomicsA comprehensive assessment of somatic mutation detection in cancer using whole genome sequencing
As whole genome sequencing for cancer genome analysis becomes a clinical tool, a full understanding of the variables affecting sequencing analysis output is required. Using tumor-normal sample pairs from two different types of cancer, chronic lymphocytic leukemia and medulloblastoma, we conducted a ...
EGAS00001001539 | EGA
UnknownEffect of SGLT2 Inhibitors on Stroke and Atrial Fibrillation in Diabetic Kidney Disease: Results From the CREDENCE Trial and Meta-Analysis.
Not available
S-EPMC8078131 | biostudies-literature
UnknownFatal and Nonfatal Events Within 14 days After Early, Intensive Mobilization Poststroke.
Not available
S-EPMC8055346 | biostudies-literature
UnknownA genetic history of the Balkans from Roman frontier to Slavic migrations.
Not available
S-EPMC10752003 | biostudies-literature
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