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GenomicsCore transcriptional regulatory circuit controlled by the tal1 complex in human t-cell acute lymphoblastic leukemia (Subseries)
The oncogenic transcription factor TAL1/SCL is aberrantly overexpressed in over 40% of cases of T-cell acute lymphoblastic leukemia (T-ALL), emphasizing the importance of the TAL1-regulated transcriptional program in the molecular pathogenesis of T-ALL. Here we identify the core transcriptional regu...
ORGANISM(S): Homo sapiens 
2012-03-14 | E-GEOD-33850 | biostudies-arrayexpress
UnknownGene Polymorphisms Increasing the Risk of Intracranial Aneurysms: Interleukin-1β -511C>T (Part I).
Not available
S-EPMC9179052 | biostudies-literature
GenomicsExpression, ChIP-chip, and ChIP-Seq data from REH and SEM leukemia cell lines [ChIP-Seq]
MLL-fusion proteins are potent inducers of cancer in hematopoietic cells, where they are known to cause changes in global gene expression. How MLL-fusion proteins interact with the genome has not been established, so we have limited understanding of the pathway by which these proteins generate aberr...
ORGANISM(S): Homo sapiens 
2012-05-31 | E-GEOD-38338 | biostudies-arrayexpress
TranscriptomicsExpression and ChIP-chip data from REH and SEM leukemia cell lines
MLL-fusion proteins are potent inducers of cancer in hematopoietic cells, where they are known to cause changes in global gene expression. How MLL-fusion proteins interact with the genome has not been established, so we have limited understanding of the pathway by which these proteins generate aber...
ORGANISM(S): Homo sapiens 
2008-12-14 | E-GEOD-13313 | biostudies-arrayexpress
UnknownRoles of Nicotine in the Development of Intracranial Aneurysm Rupture.
Not available
S-EPMC6214667 | biostudies-literature
UnknownThe impact of viral mutations on recognition by SARS-CoV-2 specific T cells.
Not available
S-EPMC8552693 | biostudies-literature
UnknownSmartphone motor testing to distinguish idiopathic REM sleep behavior disorder, controls, and PD.
Not available
S-EPMC6202945 | biostudies-literature
ProteomicsMulti-omics profiling of hypertrophic cardiomyopathy reveals altered mechanisms in mitochondrial dynamics and excitation-contraction coupling
Hypertrophic cardiomyopathy is one of the most common inherited cardiomyopathies, and a leading cause of sudden cardiac death in young adults. Despite profound insights into the genetics, there is imperfect correlation between mutation and clinical prognosis, suggesting complex molecular cascades dr...
ORGANISM(S): Homo sapiens (Human) 
2023-05-10 | PXD039613 | Pride
Myectomy Hipsc-cm Hcm 
UnknownNeutrophil Extracellular Traps Promote the Development of Intracranial Aneurysm Rupture.
Not available
S-EPMC8208639 | biostudies-literature
UnknownPotential Influences of Gut Microbiota on the Formation of Intracranial Aneurysm.
Not available
S-EPMC6530585 | biostudies-literature
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