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GenomicsMetamycoplasma hominis ATCC 27545 strain:LBD-4
Metamycoplasma hominis ATCC 27545 strain:LBD-4 Genome sequencing
PRJNA264054 | ENA
GenomicsSingle nucleus RNA sequencing data of Lewy Body Dementia (LBD) brains
Single nucleus RNA sequencing data of Lewy Body Dementia (LBD) brains
PRJNA988028 | ENA
GenomicsCD4+ T cells contribute to neurodegeneration in Lewy body dementia [CSF_and_PBMCs_Healthy and LBD]
CD4+ T cells contribute to neurodegeneration in Lewy body dementia [CSF_and_PBMCs_Healthy and LBD]
PRJNA593998 | ENA
ProteomicsAlzheimer’s Disease (AD) and Lewy Body Dementia (LBD): Detection of S-Nitrosylation in Key Proteins in Human, Post-mortem Brain Samples
FAD and Lewy Body Dementia (LBD): Detection of S-Nitrosylation in Key Proteins in Human, Post-mortem Brain Samples
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD020945 | Pride
Lbd Ad Lc-ms2 
TranscriptomicsSingle nucleus RNA sequencing data of Lewy Body Dementia (LBD) brains
Aggregated α-synuclein (α-SYN) proteins, encoded by the SNCA gene, are hallmarks of Lewy body disease (LBD), affecting multiple brain regions. However, the specific mechanisms underlying α-SYN pathology in cortical neurons, crucial for LBD-associated dementia, remain unclear. Here, we generated huma...
ORGANISM(S): Homo sapiens 
2024-09-18 | GSE235914 | GEO
TranscriptomicsCD4+ T cells contribute to neurodegeneration in Lewy body dementia [CSF_and_PBMCs_Healthy and LBD]
Recent studies indicate that the adaptive immune system plays a role in Lewy body dementia (LBD). However, the mechanism regulating T cell brain homing in LBD is unknown. Here, we observed T cells adjacent to Lewy bodies and dopaminergic neurons in post-mortem LBD brains. Single-cell RNA sequencing ...
ORGANISM(S): Homo sapiens 
2021-09-14 | GSE141578 | GEO
GenomicsTargeting the ERα DBD-LBD interface with mitoxantrone disrupts receptor function through proteasomal degradation
Targeting the ERα DBD-LBD interface with mitoxantrone disrupts receptor function through proteasomal degradation
PRJNA1295824 | ENA
GenomicsEnhanced woody biomass production in hybrid aspen through xylem-specific overexpression of Arabidopsis thaliana LBD genes
Enhanced woody biomass production in hybrid aspen through xylem-specific overexpression of Arabidopsis thaliana LBD genes
PRJNA1379629 | ENA
TranscriptomicsTargeting the ERα DBD-LBD interface with mitoxantrone disrupts receptor function through proteasomal degradation
The estrogen receptor (ER or ERα) remains the primary therapeutic target for luminal breast cancer, with current treatments centered on competitive antagonists, receptor down-regulators, and aromatase inhibitors. This therapeutic landscape frames our discovery of an alternative mechanism of ER inhib...
ORGANISM(S): Homo sapiens 
2025-07-24 | GSE303561 | GEO
UnknownLBD: a manually curated database of experimentally validated lymphoma biomarkers.
Not available
S-EPMC9254641 | biostudies-literature
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