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ProteomicsMBD8 is required for LDL2-mediated transcriptional repression downstream of H3K9me2 in Arabidopsis
Histone H3 lysine 9 methylation (H3K9me) is a conserved epigenetic mark for transcriptional gene repression. In Arabidopsis, H3K9 dimethylation (H3K9me2) promotes the removal of a transcription-associated mark, H3K4 monomethylation (H3K4me1), and this process within genes requires the histone demeth...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2026-06-08 | PXD069014 | Pride
Arabidopsis Ldl2 Mbd8 
TranscriptomicsArabidopsis thaliana seedlings: Wild type vs. sdg26, atx1, sdg25, clf, ldl1 ldl2 and combined mutants
Transcriptional profiling of 16-day-old seedlings of Arabidopsis wild type control and mutants is performed using AligentM-bM-^@M-^Ys Whole Arabidopsis Gene Expression Microarray (4x44K). Two-condition experiment, seedlings of wild type control vs. Mutant sdg25, sdg26, sdg25 sdg26, atx1, sdg26 atx1,...
ORGANISM(S): Arabidopsis thaliana 
2014-12-22 | E-GEOD-55167 | biostudies-arrayexpress
GenomicsMBD8 acts a conserved cofactor of the histone demethylase LDL2 to regulate flowering time in plants [LDL2_RNAseq]
MBD8 acts a conserved cofactor of the histone demethylase LDL2 to regulate flowering time in plants [LDL2_RNAseq]
PRJNA1438055 | ENA
GenomicsMBD8 acts a conserved cofactor of the histone demethylase LDL2 to regulate flowering time in plants [LDL2_ChIPseq]
MBD8 acts a conserved cofactor of the histone demethylase LDL2 to regulate flowering time in plants [LDL2_ChIPseq]
PRJNA1438062 | ENA
TranscriptomicsMBD8 acts a conserved cofactor of the histone demethylase LDL2 to regulate flowering time in plants [LDL2_RNAseq]
Histone demethylases have been extensively characterized in plants, yet how their enzymatic activities are regulated remains largely unknown. Here, we identify that MBD8, a protein harboring a putative methyl-CpG-binding domain (MBD), forms a protein complex with the histone demethylase LDL2 in Arab...
ORGANISM(S): Arabidopsis thaliana Oryza sativa 
2026-06-01 | GSE324891 | GEO
GenomicsMBD8 acts a conserved cofactor of the histone demethylase LDL2 to regulate flowering time in plants [LDL2_ChIPseq]
Histone demethylases have been extensively characterized in plants, yet how their enzymatic activities are regulated remains largely unknown. Here, we identify that MBD8, a protein harboring a putative methyl-CpG-binding domain (MBD), forms a protein complex with the histone demethylase LDL2 in Arab...
ORGANISM(S): Arabidopsis thaliana 
2026-06-01 | GSE324890 | GEO
TranscriptomicsThe SET-domain protein SUVR5 mediates H3K9me2 deposition and silencing at stimulus response genes in a DNA methylation independent manner
In eukaryotic cells, environmental and developmental signals alter chromatin structure and modulate gene expression. Heterochromatin constitutes the transcriptionally inactive state of the genome and in plants and mammals is generally characterized by DNA methylation and histone modifications such a...
ORGANISM(S): Arabidopsis thaliana 
2013-08-26 | E-GEOD-39405 | biostudies-arrayexpress
TranscriptomicsThe SET-domain protein SUVR5 mediates H3K9me2 deposition and silencing at stimulus response genes in a DNA methylation independent manner [RNA-Seq]
In eukaryotic cells, environmental and developmental signals alter chromatin structure and modulate gene expression. Heterochromatin constitutes the transcriptionally inactive state of the genome and in plants and mammals is generally characterized by DNA methylation and histone modifications such a...
ORGANISM(S): Arabidopsis thaliana 
2014-06-06 | E-GEOD-58029 | biostudies-arrayexpress
GenomicsArabidopsis thaliana
Arabidopsis thaliana seedlings: Wild type vs. sdg26, atx1, sdg25, clf, ldl1 ldl2 and combined mutants
PRJNA238807 | ENA
GenomicsGlycine max
Glycine max histone demethylase-LDL2 regulates flowering time via FERONIA for regional adaptation (PRJCA031230)
PRJDB36336 | ENA
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