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ProteomicsMBD8 is required for LDL2-mediated transcriptional repression downstream of H3K9me2 in Arabidopsis
Histone H3 lysine 9 methylation (H3K9me) is a conserved epigenetic mark for transcriptional gene repression. In Arabidopsis, H3K9 dimethylation (H3K9me2) promotes the removal of a transcription-associated mark, H3K4 monomethylation (H3K4me1), and this process within genes requires the histone demeth...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2026-06-08 | PXD069014 | Pride
Arabidopsis Ldl2 Mbd8 
GenomicsMBD8 acts a conserved cofactor of the histone demethylase LDL2 to regulate flowering time in plants [LDL2_RNAseq]
MBD8 acts a conserved cofactor of the histone demethylase LDL2 to regulate flowering time in plants [LDL2_RNAseq]
PRJNA1438055 | ENA
GenomicsMBD8 acts a conserved cofactor of the histone demethylase LDL2 to regulate flowering time in plants [LDL2_ChIPseq]
MBD8 acts a conserved cofactor of the histone demethylase LDL2 to regulate flowering time in plants [LDL2_ChIPseq]
PRJNA1438062 | ENA
TranscriptomicsMBD8 acts a conserved cofactor of the histone demethylase LDL2 to regulate flowering time in plants [LDL2_RNAseq]
Histone demethylases have been extensively characterized in plants, yet how their enzymatic activities are regulated remains largely unknown. Here, we identify that MBD8, a protein harboring a putative methyl-CpG-binding domain (MBD), forms a protein complex with the histone demethylase LDL2 in Arab...
ORGANISM(S): Arabidopsis thaliana Oryza sativa 
2026-06-01 | GSE324891 | GEO
GenomicsMBD8 acts a conserved cofactor of the histone demethylase LDL2 to regulate flowering time in plants [LDL2_ChIPseq]
Histone demethylases have been extensively characterized in plants, yet how their enzymatic activities are regulated remains largely unknown. Here, we identify that MBD8, a protein harboring a putative methyl-CpG-binding domain (MBD), forms a protein complex with the histone demethylase LDL2 in Arab...
ORGANISM(S): Arabidopsis thaliana 
2026-06-01 | GSE324890 | GEO
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