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ProteomicsChemoproteomic target deconvolution of Lipoic acid reveals Histone Deacetylases as the main targets
Here we set out to identify protein targets of Lipoic acid and Lipoamide by chemical proteomics approaches. We generated Lipoamide-based affinity matrices to pulldown target proteins and quantify them via bottom-up proteomics. Use of the same affinity matrix in dose dependent compeition assays allow...
ORGANISM(S): Homo sapiens (Human) 
2026-06-02 | PXD036810 | Pride
Lc-msms Drug target deconvolution Cancer cell lines 
TranscriptomicsFF and FFPE HPV+ and HPV- HNSCC and HNSCC cell lines
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2012-11-30 | E-GEOD-38271 | biostudies-arrayexpress
UnknownChemoproteomic target deconvolution reveals Histone Deacetylases as targets of (R)-lipoic acid.
Not available
S-EPMC10272112 | biostudies-literature
GenomicsMethylome Analysis of FF HPV+ and HPV- HNSCC samples
The analysis of the 6 methylomes by MeDIP-Seq comprise 3 HPV+ HNSCC samples and 3 HPV- HNSCC samples Analysis of the 6 methylomes, comprising 3 HPV+ HNSCC samples and 3 HPV- HNSCC samples
ORGANISM(S): Homo sapiens 
2012-11-01 | E-GEOD-38263 | biostudies-arrayexpress
Transcriptomics450k Analysis of 3 FF HPV+ and 3 FF HPV- HNSCC samples
The methylation analysis of 3 FF HPV+ HNSCC samples and 21 FP HPV- HNSCC samples by Infinium HumanMethylation450 BeadChip Analysis of 6 450k methylation profiles, comprising 3 HPV+ HNSCC samples and 3 HPV- HNSCC samples
ORGANISM(S): Homo sapiens 
2012-11-30 | E-GEOD-38268 | biostudies-arrayexpress
Transcriptomics450k Analysis of 42 FFPE HPV+ and HPV- HNSCC samples
The methylation analysis of 21 FFPE HPV+ HNSCC samples and 21 FPPE HPV- HNSCC samples by Infinium HumanMethylation450 BeadChip Analysis of 42 450k methylation profiles, comprising 21 HPV+ HNSCC samples and 21 HPV- HNSCC samples
ORGANISM(S): Homo sapiens 
2012-11-30 | E-GEOD-38266 | biostudies-arrayexpress
Transcriptomics450k Analysis of 24 HNSCC cell lines
The methylation analysis of HPV+ HNSCC cell lines and HPV- HNSCC cell lines as well as clones from an infected HPV- cell line by Infinium HumanMethylation450 BeadChip Analysis of 24 450k methylation profiles, comprising 3 HPV+ HNSCC cell lines and 3 HPV- HNSCC cell lines (in duplicate each) and 12 i...
ORGANISM(S): Homo sapiens 
2012-11-30 | E-GEOD-38270 | biostudies-arrayexpress
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