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UnknownGlobal Phosphoproteomics Reveal CDK Suppression as a Vulnerability to KRas Addiction in Pancreatic Cancer.
Not available
S-EPMC8493485 | biostudies-literature
UnknownDevelopment of a hybrid model for a partially known intracellular signaling pathway through correction term estimation and neural network modeling.
Not available
S-EPMC7769624 | biostudies-literature
UnknownAI-Radiomics Can Improve Inclusion Criteria and Clinical Trial Performance.
Not available
S-EPMC8880510 | biostudies-literature
TranscriptomicsThe ability of VSL#3 to restore the age-related deficit in LTP is associated with changes in brain genes expression
A deficit in synaptic plasticity is one of the many changes that occurs with age. Specifically the archetypal model of plasticity, long-term potentiation (LTP), is reduced in hippocampus of middle-aged and aged animals. Several factors are likely to contribute to this deficit including morphologic...
ORGANISM(S): Rattus norvegicus 
2014-04-02 | E-GEOD-51381 | biostudies-arrayexpress
UnknownTowards Next-Generation Sequencing for HIV-1 Drug Resistance Testing in a Clinical Setting.
Not available
S-EPMC9608942 | biostudies-literature
UnknownStandardization in Quantitative Imaging: A Multicenter Comparison of Radiomic Features from Different Software Packages on Digital Reference Objects and Patient Data Sets.
Not available
S-EPMC7289262 | biostudies-literature
ProteomicsGlobal Lysine Acetylome Analysis of LPS-Stimulated HepG2 Cells Identifies Hyperacetylation of PKM2 as a Metabolic Reg-ulator in Sepsis
Sepsis-induced liver dysfunction is a frequent event and is strongly associated with mortality. Establishing a causative link between protein post-translational modification (PTM) and diseases is challenging. We studied the relationship among the lysine acetylation (Kac), the sirtuin (SIRTs), and th...
ORGANISM(S): Homo sapiens (Human) 
2024-01-30 | PXD027496 | Pride
Sepsis-induced liver dysfunction  hyperacetylation  sirt  lysine acetylation  pyruvate kinase m2 
TranscriptomicsInhibition of the mitochondrial electron transport chain by antimycin A in Arabidopsis thaliana
Plant mitochondria signal to the nucleus leading to altered transcription of nuclear genes by a process called mitochondrial retrograde regulation (MRR). MRR is implicated in metabolic homeostasis and responses to stress conditions. Transcriptional consequences on nuclear gene expression of mitochon...
ORGANISM(S): Arabidopsis thaliana 
2013-01-01 | E-GEOD-29204 | biostudies-arrayexpress
ProteomicsThe GATOR2–mTORC2 axis mediates Sestrin2-induced AKT Ser/Thr kinase activation
Sestrins represent a family of stress-inducible proteins that prevent the progression of many age- and obesity-associated disorders. Endogenous Sestrins maintain insulin-dependent AKT Ser/Thr kinase (AKT) activation during high-fat diet (HFD)-induced obesity, and overexpressed Sestrins activate AKT ...
ORGANISM(S): Homo sapiens (Human) 
2020-01-15 | PXD015824 | Pride
Sestrin2 Akt pkb Liver metabolism Gator2 Mtor 
UnknownMachine learning model optimization for flood susceptibility zonation over the Kosi megafan, Himalayan foreland basin, India.
Not available
S-EPMC12460597 | biostudies-literature
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