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GenomicsConduritol B Epoxide treatment of MSCs and 293T cells
Conduritol B Epoxide treatment of MSCs and 293T cells
PRJNA110421 | ENA
GenomicBuphenyl and Low-Dose Arginine Vs. High-Dose Arginine in Patients with ASA

Individuals with Urea Cycle Disorders (UCD) cannot remove ammonia, a waste product, from the blood. At present there is little information on the use of sodium phenylbutyrate (Buphenyl™) in children with argininosuccinic aciduria (ASA). It is hoped that this drug may help lower ammonia and ...

phs001305 | dbGaP
TranscriptomicsmiR-122 as a Regulator of Mitochondrial Metabolic Gene Network in Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) is the leading cause of cancer-related deaths worldwide, reflecting the need for a better understanding of hepatocarcinogenesis. In this study, we examined the genome-wide expression profiles of both miRNAs and mRNAs from paired tumor and adjacent non-tumor tissues fro...
ORGANISM(S): Homo sapiens 
2010-06-09 | E-GEOD-22058 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mice hearts comparing microRNA-22 overexpression to wildtype
To explore the role of miR-22 in the heart, we generated miR-22 null and transgenic mice. Cardiac transgenic overexpression of miR-22 in vivo led to cardiac hypertrophy that evolved into progressive dilated cardiomyopathy (DCM) in unstressed hearts. We found that miR-22 directly regulates two transc...
ORGANISM(S): Mus musculus 
2012-12-01 | E-MTAB-501 | biostudies-arrayexpress
TranscriptomicsNotch-HES1 signaling axis controls hemato-endothelial fate decisions of human embyronic and induced pluripotent cells
Notch signaling regulates several cellular processes including cell fate decisions and proliferation in both invertebrates and mice. However, comparatively less is known about the role of Notch during early human development. Here, we examined the function of Notch signaling during hematopoietic lin...
ORGANISM(S): Homo sapiens 
2013-06-01 | E-GEOD-47466 | biostudies-arrayexpress
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