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TranscriptomicsTranscription profiling of liver from hypothyroid mice pups produced from dams given 6-propyl-2-thiouracil (PTU) in their drinking water
Pregnant dams were treated with 0.1% or 0.04% 6-propyl-2-thiouracil (PTU) in drinking water continuously from day 13 post conception until weaning to produce hypothyroid pups. livers were collected from vehicle and 0.1% PTU treated pups at post-natal day (PND) 15 and mRNA from these was subjected to...
ORGANISM(S): Mus musculus 
2007-05-03 | E-MEXP-1091 | biostudies-arrayexpress
TranscriptomicsSystems toxicology assessment of a representative e-liquid formulation using human primary bronchial epithelial cells
The development of reduced-risk products is aimed at providing adult smokers, who are unable to quit, with alternatives to cigarettes that present less risk of harm and smoking-related disease. The use of flavors in the development of these reduced-risk products fulfils an important role in product ...
ORGANISM(S): Homo sapiens 
2019-11-01 | E-MTAB-7748 | biostudies-arrayexpress
MetabolomicsMetabolic analysis of the response of Pseudomonas putida DOT-T1E strains to toluene using Fourier transform infrared spectroscopy and gas chromatography mass spectrometry
To elucidate any observable metabolic alterations during interactions of several strains of Pseudomonas putida (DOT-T1E, and its mutants DOT-T1E-PS28 and DOT-T1E-18) with the aromatic hydrocarbon toluene, metabolomic approaches were employed. Initially, Fourier-transform infrared (FT-IR) spectroscop...
2016-08-23 | MTBLS319 | MetaboLights
UnknownDevelopment and Validation of Nomograms Predictive of Overall and Progression-Free Survival in Patients With Oropharyngeal Cancer.
Not available
S-EPMC5736236 | biostudies-literature
TranscriptomicsATAC-seq of liver of a Holstein Friesian infant male.
We performed the assay for transposase-accessible chromatin using sequencing (ATAC-seq) on a liver sample collected from one Holstein Friesian healthy male at one month of age to profile open chromatin regions genome-wide to identify putative regulatory elements related to phenotype of interest.
ORGANISM(S): Bos taurus 
2021-07-09 | E-MTAB-9872 | biostudies-arrayexpress
TranscriptomicsStranded Total RNA-seq of liver biopsy collected from Holstein Friesian cows
To explore potential functional genes related to milk production traits in cow, we performed total RNA-seq using liver biospy collected from 77 Holstein Friesian cows at postpartum 2 weeks.
ORGANISM(S): Bos taurus 
2021-07-09 | E-MTAB-9871 | biostudies-arrayexpress
TranscriptomicsTimed induction of 50 transcription factors in ES cells reveals a common mechanism to initiate differentiations
To decipher the structure and behaviors of the transcription factor (TF) network, we created 50 permanent mouse ES cell lines, in each of which one of the 50 transcription factors tagged with FLAG, is inserted into the doxycycline (dox)-repressible ROSA26 locus. Expression profiling reveals Cdx2 as ...
ORGANISM(S): Mus musculus 
2009-10-01 | E-GEOD-14559 | biostudies-arrayexpress
UnknownWhole genome sequence analyses of brain imaging measures in the Framingham Study.
Not available
S-EPMC5772158 | biostudies-literature
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