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UnknownPhase III randomized trial of weekly cisplatin and irradiation versus cisplatin and tirapazamine and irradiation in stages IB2, IIA, IIB, IIIB, and IVA cervical carcinoma limited to the pelvis: a Gynecologic Oncology Group study.
Not available
S-EPMC3912330 | biostudies-literature
TranscriptomicsTranscription profiling of human HCT116 PTEN+/+ cell lines and three independently-derived HCT116 PTEN-/- cell lines
In an effort to identify genes whose expression is regulated by activated PI3K signaling, we performed microarray analysis and subsequent qRT-PCR on an isogenic set of PTEN gene-targeted human cancer cells. Numerous p53 effectors were upregulated following PTEN deletion, including p21, GDF15, PIG3, ...
ORGANISM(S): Homo sapiens 
2008-06-14 | E-GEOD-6263 | biostudies-arrayexpress
UnknownCirculating tumour mutation detection in triple-negative breast cancer as an adjunct to tissue response assessment.
Not available
S-EPMC10770342 | biostudies-literature
UnknownPKCζ mediates disturbed flow-induced endothelial apoptosis via p53 SUMOylation
Not available
S-JCBD-201010051 | bioimages
TranscriptomicsWhite-to-brown metabolic conversion of human adipocytes by JAK inhibition
The rising incidence of obesity and related disorders such as diabetes and heart disease has focused considerable attention on the discovery of novel therapeutics. One promising approach has been to increase the number or activity of brown-like adipocytes in white adipose depots, as this has been...
ORGANISM(S): Homo sapiens 
2014-10-31 | E-GEOD-57896 | biostudies-arrayexpress
UnknownRiluzole, a glutamate modulator, slows cerebral glucose metabolism decline in patients with Alzheimer's disease.
Not available
S-EPMC8719848 | biostudies-literature
TranscriptomicsControl of Somatic Tissue Differentiation by the Long Non-Coding RNA TINCR (array)
Several of the thousands of human long non-coding RNAs (lncRNAs) have been functionally characterized; however, potential roles for lncRNAs in somatic tissue differentiation remain poorly understood. Here we show that a 3.7kb lncRNA, terminal differentiation-induced ncRNA (TINCR), controls human ...
ORGANISM(S): Homo sapiens 
2012-10-10 | E-GEOD-40122 | biostudies-arrayexpress
UnknownWithholding or withdrawing life-sustaining treatment in extremely low gestational age neonates.
Not available
S-EPMC8055718 | biostudies-literature
UnknownWhole genome sequence analyses of brain imaging measures in the Framingham Study.
Not available
S-EPMC5772158 | biostudies-literature
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