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MetabolomicsAn Unbiased Lipid Phenotyping Approach To Study the Genetic Determinants of Lipids and Their Association with Coronary Heart Disease Risk Factors
Direct infusion high-resolution mass spectrometry (DIHRMS) is a novel, high-throughput approach to rapidly and accurately profile hundreds of lipids in human serum without prior chromatography, facilitating in-depth lipid phenotyping for large epidemiological studies to reveal the detailed associati...
2024-02-02 | MTBLS4461 | MetaboLights
UnknownA Stiff Injectable Biodegradable Elastomer.
Not available
S-EPMC3646576 | biostudies-literature
UnknownDraft Genome Sequences of Six Enterococcus faecalis Strains Isolated from Malaysian Clinical and Environmental Origins.
Not available
S-EPMC5473281 | biostudies-literature
MetabolomicsRepurposing the orphan drug nitisinone to control the transmission of African trypanosomiasis
Tsetse transmit African trypanosomiasis, which is a disease fatal to both humans and animals. A vaccine to protect against this disease does not exist so transmission control relies on eliminating tsetse populations. Although neurotoxic insecticides are the gold standard for insect control, they neg...
2021-10-06 | MTBLS2166 | MetaboLights
TranscriptomicspiRNA-guided slicing of transposon transcripts enforces their transcriptional silencing via specifying the nuclear piRNA repertoire
PIWI-clade Argonaute proteins silence transposon expression in animal gonads. Their target specificity is defined by bound ~23-30nt piRNAs that are processed from single-stranded precursor transcripts via two distinct pathways. Primary piRNAs are defined by the endo-nuclease Zucchini, while biogenes...
ORGANISM(S): Drosophila melanogaster 
2015-08-31 | E-GEOD-71775 | biostudies-arrayexpress
UnknownVaccination with patient-specific tumor-derived antigen in first remission improves disease-free survival in follicular lymphoma.
Not available
S-EPMC3139394 | biostudies-literature
GenomicsChIP-seq of CTCF, RAD21, and TOP2B binding sites in three human tissue samples with hepatocellular carcinoma
The roles of topoisomerases in somatic mutagenesis in cancer are poorly understood and their DNA-binding landscape remains largely unmapped. Here we generated genome-wide DNA-binding maps of TOP2B, CTCF, and RAD21 in human hepatocellular carcinoma samples.
ORGANISM(S): Homo sapiens 
2024-02-01 | E-MTAB-13301 | biostudies-arrayexpress
TranscriptomicsC. elegans piRNAs are processed from capped-small RNAs transcribed at promoters throughout the genome
Piwi-interacting (pi) RNAs are a class of germline-expressed small RNAs that have been linked to epigenetic programming in metazoa. C. elegans piRNAs known as 21U-RNAs are defined by more than 15,000 genome-encoded species. To explore the origin of 21U-RNAs we employed methods to enrich the 5' ends ...
ORGANISM(S): Mus musculus 
2012-12-22 | E-GEOD-40053 | biostudies-arrayexpress
no omics definedGenotyping of twenty Pseudomonas aeruginosa strains
20 P. aeruginosa strains were genotyped using a custom spotted oligo array (Ausubel P. aruginosa genotyping 4.8K v1), which included primarily oligos for genes present in strain PA14 but absent in PAO1, and oligos for genes present in PAO1 but absent in PA14 (as well as controls).
ORGANISM(S): Pseudomonas aeruginosa 
2006-10-06 | E-MEXP-824 | biostudies-arrayexpress
TranscriptomicsElimination of hydrogenase post-translational modification blocks H2 production and increases ethanol yield in Clostridium thermocellum
Clostridium thermocellum is a leading candidate organism for implementing a consolidated bioprocessing (CBP) strategy for biofuel production due to its native ability to rapidly consume cellulose and its existing ethanol production pathway. C. thermocellum converts cellulose and cellobiose to lactat...
ORGANISM(S): Clostridium thermocellum DSM 1237 
2014-01-15 | E-GEOD-54082 | biostudies-arrayexpress
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