Lee David C DC - OmicsDI

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Unknown (195)
Genomics (37)
Proteomics (6)
Metabolomics (4)
Transcriptomics (1)

Organisms

Homo sapiens (37)
Mycobacterium tuberculosis SP7 (5)
Mycobacterium tuberculosis SP10 (5)
Mycobacterium tuberculosis SP13 (5)
Mycobacterium tuberculosis SP22 (5)
Chlamydomonas reinhardtii (5)
Enterococcus mundtii CRL35 (5)
Oncorhynchus tshawytscha (5)
Pseudomonas canadensis (5)
Pseudomonas aeruginosa PAO1H2O (5)
Human alphaherpesvirus 1 strain 17 (5)
Mycobacterium tuberculosis SP1 (5)
Marchantia polymorpha subsp. ruderalis (5)
Methylocystis sp. (5)
Exiguobacterium sp. SH31 (5)
Palaemonetes sp. common grass shrimp associated circular virus (5)
Amaranthus tricolor (5)
Spirochaeta sp. ELBA (5)
Clavibacter nebraskensis NCPPB 2581 (5)
Porites pukoensis (5)
Porphyromonas gingivalis (5)
Leishmania tarentolae (5)
Porphyromonas gingivalis W83 (5)
Human betaherpesvirus 5 (5)
Bothrops insularis (5)
Bothrops jararaca (5)
Bothrops jararacussu (5)
Bothrops cotiara (5)
Acinetobacter baumannii ATCC 19606 = CIP 70.34 = JCM 6841 (5)
Mus musculus (1)

Repository

EGA (37)
pride (5)
MetaboLights (4)
biostudies-arrayexpress (1)
MassIVE (1)

Tissue

Heart (1)
Liver (1)

Disease

Amyotrophic lateral sclerosis (1)

Technology Type

Mass Spectrometry (5)
Mass spectrometry (4)
Chemical cross-linking coupled with mass spectrometry proteomics (3)
AB 5500 Genetic Analyzer, Ion Torrent PGM (1)
Illumina HiSeq 1000, Ion Torrent PGM, Illumina Genome Analyzer IIx (1)
Illumina HiSeq 2000 (1)
Affinity purification coupled with mass spectrometry proteomics (1)
Shotgun proteomics (1)

Instrument Platform

Q Exactive Plus (1)
Direct infusion MS - negative (1)
Agilent 5975E GC/MSD (Agilent) (1)
Direct infusion MS - positive (1)
Exactive (Thermo Scientific) (1)
Liquid Chromatography MS - positive - reverse phase (1)

Publication Date

2025 (4)
2019 (2)
2014 (1)
2017 (1)
2016 (1)
2022 (1)
2021 (1)

CHEBI ID

CHEBI:17992 (2)
CHEBI:17822 (2)
CHEBI:25094 (2)
CHEBI:22660 (2)
CHEBI:28757 (2)
CHEBI:26986 (2)
CHEBI:28300 (2)
CHEBI:18257 (2)
CHEBI:15428 (2)
CHEBI:17754 (2)
CHEBI:16119 (2)
CHEBI:15741 (2)
CHEBI:28044 (2)
CHEBI:16865 (2)
CHEBI:16010 (2)
CHEBI:27897 (2)
CHEBI:15756 (2)
CHEBI:30769 (2)
CHEBI:132192 (1)
CHEBI:90140 (1)
CHEBI:132185 (1)
CHEBI:132184 (1)
CHEBI:132177 (1)
CHEBI:62805 (1)
CHEBI:132187 (1)
CHEBI:43619 (1)
CHEBI:131420 (1)
CHEBI:111510 (1)
CHEBI:132176 (1)
CHEBI:34856 (1)

Metabolite Name

1H-Indole, 1-(trimethylsilyl)-3-[2-[(trimethylsilyl)oxy]ethyl]- (1)
N,N-bis [2-Trimethylsiloxyethyl] ethanamine (1)
Beta-D-Galactopyranoside, methyl 2,3-bis-O-(trimethylsilyl)-, diacetate (1)
1-Cyclohexene-1-carboxylic acid, 3,4,5-tris[(trimethylsilyl)oxy]-, trimethylsilyl ester, [3R-(3alpha,4alpha,5beta)]- (1)
Myo-Inositol, 1,2,3,4,5,6-hexakis-O-(trimethylsilyl)- (1)
2-Naphthyl-beta-D-galactopyranoside (1)
D-Erythrotetrofuranose, tris-O-(trimethylsilyl)- (1)
Galactopyranose, 1,2,3,4,6-pentakis-O-(trimethylsilyl)-, beta-d- (1)
D-Galactose, 2,3,4,5,6-pentakis-O-(trimethylsilyl)- (1)
1-Butanone, 2-chloro-3-methyl-1-[4-(1-methylethyl)phenyl]- (1)
N,O-Bis-(trimethylsilyl)isoleucine (1)
Propanoic acid, 2-methyl-2-[(trimethylsilyl)oxy]-, trimethylsilyl ester (1)
Benzeneethanamine, N,alpha-dimethyl-beta-[(trimethylsilyl)oxy]- (1)
N,O-Bis-(trimethylsilyl)-2-pyrrolidone carboxylic acid (1)
2-Piperidinecarboxylic acid, 1-(trimethylsilyl)-, trimethylsilyl ester (1)
L-Leucine, N-(trimethylsilyl)-, trimethylsilyl ester (1)
Alpha-D-Mannopyranose, 1,2,3,4,6-pentakis-O-(trimethylsilyl)- (1)
Silanamine, N-[2-[3,4-bis[(trimethylsilyl)oxy]phenyl]ethyl]-1,1,1-trimethyl-N-(trimethylsilyl)- (1)
L-Aspartic acid, N-(trimethylsilyl)-, bis(trimethylsilyl) ester (1)
Butanoic acid, 2,4-bis[(trimethylsilyl)oxy]-, trimethylsilyl ester (1)
Glycine d5 (1)
L-Isoleucine, N-(trimethylsilyl)-, trimethylsilyl ester (1)
Silanamine, 1,1,1-trimethyl-N-(trimethylsilyl)-N-[2-[(trimethylsilyl)oxy]ethyl]- (1)
Pyridine, 3-trimethylsiloxy- (1)
Trisiloxane, 1,1,1,5,5,5-hexamethyl-3,3-bis[(trimethylsilyl)oxy]- (1)
4-(Trimethylsilyl)morpholine (1)
Pyridine, 3-methyl- (1)
Glycine, N-(trimethylsilyl)-, trimethylsilyl ester (1)
Cyclopentanecarboxylic acid, 1-amino-, bis(trimethylsilyl) deriv. (1)
Triethylamine, 2-chloro-2'-(trimethyl)silyloxy- (1)

Study type

Transcription profiling by array (1)

Release Date

2022 (27)
2021 (24)
2023 (22)
2025 (20)
2024 (17)
2020 (13)
2015 (10)
2013 (10)
2026 (8)
2017 (8)
2014 (7)
2019 (6)
2016 (6)
2018 (5)
2011 (5)
2012 (4)
2010 (3)
2008 (1)

Lab affiliation

Biochemistry & Molecular Biology, Cumming School of Medicine, University of Calgary Department of Chemistry, University of Calgary (1)
Department of Biology, University of Konstanz, Universitaetsstrasse 10, 78457 Konstanz, Germany (1)
Department of Biochemistry and Molecular Biology, University of Calgary, Alberta, Canada (1)
George & Charmaine Mallinckrodt Professor Department of Biology Washington University in St. Louis (1)
University of Wisconsin-Madison (1)

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Pptc7 is an essential phosphatase for promoting mammalian mitochondrial metabolism and biogenesis

Mitochondrial proteins are replete with phosphorylation; however, the origin, abundance, and functional relevance of these modifications are largely unclear. Nonetheless, mitochondria possess multiple resident phosphatases, suggesting that protein dephosphorylation may be broadly important for mitoc...

ORGANISM(S): Mus musculus (Mouse)

2019-05-29 | PXD012743 | Pride

Functional phenotypes alteration on dendritic cells between tolerance and immnunity

Dendritic cells (DC) are key regulators of immunological responses, immunity and tolerance. Due to their differentiation capacities, they have emerged as a promising tool for therapeutic applications. However, there are poorly understood functional DC-specific markers and cellular mechanisms for in-...

ORGANISM(S): Mus musculus

2014-07-26 | E-GEOD-59754 | biostudies-arrayexpress

HERPES SIMPLEX VIRUS TYPE 1 IMPAIRS DENDRITIC CELL FUNCTION BY REMODELLING NEUTRAL LIPID METABOLISM AND INDUCING LIPID DROPLET ACCUMULATION

Herpes simplex virus type 1 (HSV-1) infects dendritic cells (DCs), professional antigen-presenting cells that initiate and regulate host antiviral responses. HSV-1 infects DCs limiting their maturation, migration to draining lymph nodes and T cell activation capacity, ultimately promotes their apopt...

2025-04-03 | MTBLS5163 | MetaboLights

Crosslinking-Mass Spectrometry data for structural analysis of Doublecortin-Microtubule interaction

Doublecortin (DCX) is a microtubule (MT) associated protein that regulates MT structure and function during neuronal development and mutations in DCX lead to a spectrum of neurological disorders. The structural properties of MT-bound DCX remain poorly resolved. Here, we describe the molecular archit...

ORGANISM(S): Homo sapiens (Human) Sus scrofa domesticus (domestic pig)

2022-05-04 | PXD033167 | Pride

Crosslinking-mass spectrometry Doublecortin Integrative structural modeling Microtubule

Phase I Imaging and Pharmacodynamic Trial of CS-1008 in Patients With Metastatic Colorectal Cancer.

Not available

S-EPMC4881374 | biostudies-literature

Dendritic Cell Vaccination in Conjunction with a TLR Agonist Polarizes Interferon Immune Responses in Malignant Glioma Patients.

Not available

S-EPMC10543402 | biostudies-literature

TLR agonists polarize interferon responses in conjunction with dendritic cell vaccination in malignant glioma: a randomized phase II Trial.

Not available

S-EPMC11078958 | biostudies-literature