Sort   by:  
 Page size 
TranscriptomicsDifferentiation stage-specific donor memory in induced pluripotent stem cells (iPSC) generated from hepatic lineage cells
Recent studies suggested that embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) may represent different pluripotent states as defined by gene expression profiles and differentiation potential. Here we addressed a contribution of a lineage stage-specific donor cell memory in mod...
ORGANISM(S): Mus musculus 
2012-10-02 | E-GEOD-33110 | biostudies-arrayexpress
TranscriptomicsGenomic Copy-Number Variations in Hepatoblastoma Patients Revealed by Array Comparative Genomic Hybridization
Purpose: Hepatoblastoma (HB) is a malignant pediatric hepatic progenitor cell tumor with uncertain etiology. To discover genomic biomarkers associated with this malignancy, we conduct the study. Experimental Design: A panel of ten cases and two pairs of identical twins for HB were screened using hig...
ORGANISM(S): Homo sapiens 
2010-10-01 | E-GEOD-18408 | biostudies-arrayexpress
MetabolomicsSex-dependent metabolic remodeling of kidneys revealed by arteriovenous metabolomics

Sex is a fundamental biological variable important in biomedical research, drug development, clinical trials, and prevention approaches. Among many organs, kidneys are known to exhibit remarkable structural, histological, and pathological differences between sexes. However, whether and how kidney...

2026-03-04 | MTBLS13977 | MetaboLights
UnknownErythropoietin, uncertainty principle and cancer related anaemia.
Not available
S-EPMC130027 | biostudies-literature
UnknownThe capicua-ataxin-1-like complex regulates Notch-driven marginal zone B cell development and sepsis progression.
Not available
S-EPMC11618371 | biostudies-literature
TranscriptomicsThe Two-component Signal Transduction System CopRS of Corynebacterium glutamicum is Required for Adaptation to Copper-excess Stress
Copper is an essential cofactor for many enzymes but at high concentrations it is toxic for the cell. Copper ion concentrations ≥50 µM inhibited growth of Corynebacterium glutamicum. The transcriptional response to 20 µM Cu2+ was studied using DNA microarrays and revealed 26 genes that showed a ≥3-f...
ORGANISM(S): Corynebacterium glutamicum ATCC 13032 
2011-09-04 | E-GEOD-27510 | biostudies-arrayexpress
TranscriptomicsEffect of BET inhibitors (JQ1 and RVX-208) on gene expression in HepG2 cells
Bromodomains have emerged as attractive candidates for the development of inhibitors targeting gene transcription. Inhibitors of the bromo-and-extra-terminal (BET) family recently showed promising activity in diverse disease models. However, the pleiotropic nature of BET proteins regulating tissue s...
ORGANISM(S): Homo sapiens 
2013-09-24 | E-GEOD-51143 | biostudies-arrayexpress
UnknownEffects of Home-Based Computerized Cognitive Training in Community-Dwelling Adults With Mild Cognitive Impairment.
Not available
S-EPMC10712670 | biostudies-literature
UnknownRisk Stratification Using Multivariable Fractional Polynomials in Diffuse Large B-Cell Lymphoma.
Not available
S-EPMC7078241 | biostudies-literature
MetabolomicsRegulatory T cells promote endurance exercise adaptation by shielding muscle mitochondria from damage

Exercise enhances physical performance and reduces the risk of many disorders such as cardiovascular disease, type 2 diabetes, dementia and cancer. Exercise characteristically incites an inflammatory response, notably in skeletal muscles. While some effector mechanisms have been identified, regul...

2023-10-10 | MTBLS8391 | MetaboLights
Sort   by:  
 Page size