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ProteomicsTotal proteome analysis of WT vs TRAP1 KO in HCT-116 and HEK-293T cells grown on different carbon sources.
The molecular chaperone TRAP1, the mitochondrial isoform of cytosolic HSP90, remains poorly understood with respect to its pivotal role in the regulation of mitochondrial metabolism. To characterize the impact of TRAP1 in maintaining the cellular proteome under different energy sources we carried ou...
ORGANISM(S): Homo sapiens (Human) 
2020-01-16 | PXD015828 | Pride
Oxidative phosphorylation Trap1 Mitochondrion Hsp90 Molecular chaperone 
UnknownOtotoxicity in children with high-risk neuroblastoma: prevalence, risk factors, and concordance of grading scales--a report from the Children's Oncology Group.
Not available
S-EPMC3918536 | biostudies-literature
UnknownPathways From Socioeconomic Status to Prenatal Smoking: A Test of the Reserve Capacity Model.
Not available
S-EPMC5171236 | biostudies-literature
ProteomicsSoil metaproteomics data analysis based on de novo sequencing with the deep learning-based Kaiko model
We generated a protein database directly from soil metaproteomic data by identifying the microbial composition using the Kaiko model's de novo sequencing methods. We first analyzed the mass spectra de novo (without a database), identifying species from the observed peptides. We next gathered full p...
ORGANISM(S): Environmental Samples <bacteria> (ncbitaxon:48479) 
2020-10-20 | MSV000086336 | MassIVE
TranscriptomicsIntegrated SV40 T/t-antigen Cancer Signature in Aggressive Breast, Prostate and Lung Carcinomas with Poor Prognosis
Understanding the genetic architecture of cancer pathways that distinguishes subsets of human cancer is critical to developing new therapies that better target tumors based upon their molecular expression profiles. In this study, we identify an integrated gene signature from multiple transgenic mo...
ORGANISM(S): Mus musculus 
2007-09-01 | E-GEOD-8666 | biostudies-arrayexpress
TranscriptomicsIntegrated SV40 T/t-antigen Cancer Signature in Aggressive Breast, Prostate and Lung Carcinomas with Poor Prognosis 2
Understanding the genetic architecture of cancer pathways that distinguishes subsets of human cancer is critical to developing new therapies that better target tumors based upon their molecular expression profiles. In this study, we identify an integrated gene signature from multiple transgenic mo...
ORGANISM(S): Mus musculus 
2007-09-01 | E-GEOD-8663 | biostudies-arrayexpress
TranscriptomicsIntegrated SV40 T/t-antigen Cancer Signature in Aggressive Breast, Prostate and Lung Carcinomas with Poor Prognosis 1
Understanding the genetic architecture of cancer pathways that distinguishes subsets of human cancer is critical to developing new therapies that better target tumors based upon their molecular expression profiles. In this study, we identify an integrated gene signature from multiple transgenic mo...
ORGANISM(S): Mus musculus 
2007-09-01 | E-GEOD-8662 | biostudies-arrayexpress
GenomicsPopulation Architecture using Genomics and Epidemiology (PAGE)

By relating hundreds of thousands of genotypes to only a few phenotypes, mostly in individuals of one ancestry, genome-wide association (GWA) studies are identifying a rapidly growing number of associations. The Population Architecture using Genomics and Epidemiology (PAGE) Study is designed to f...

phs000356.v1.p1 | EGA
GenomicsPopulation Architecture using Genomics and Epidemiology (PAGE): Causal Variants Across the Life Course (CALiCo): Coronary Artery Risk Development in Young Adults (CARDIA)

CALiCo CARDIA
The Coronary Artery Risk Development in Young Adults (CARDIA) Study is a study examining how heart disease develops in adults. It began in 1986 with a group of 5115 black and white men and women aged 18-30 years. The participants were selected so that there would be appr...

phs000236.v1.p1 | EGA
GenomicsPopulation Architecture using Genomics and Epidemiology (PAGE): Causal Variants Across the Life Course (CALiCo): Atherosclerosis Risk in Communities (ARIC)

CALiCo ARIC
The Atherosclerosis Risk in Communities Study (ARIC), sponsored by the National Heart, Lung and Blood Institute (NHLBI), is a prospective epidemiologic study conducted in four U.S. communities. ARIC is designed to investigate the etiology and natural history of atheroscler...

phs000223.v1.p1 | EGA
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