alpha-N-terminal methylation is an understudied post-translational modification with presumed functions involving protein-protein and/or protein-DNA interaction. The covalent addition of mono-, di-, trimethyl groups to free alpha-amino group has proven to be difficult to profile globally by mass spe...
The comparative transcriptome profiling of L-threonine producing strain (TH07 strain harboring pBRThrABC) and control W3110 (lacI-deleted) strain harboring pKK223-3 has been analyzed using oligo nucleotide microarray. Keywords: comparative transcriptome analysis (between L-threonine producing strai...
Dynamic regulation of glucose flux between aerobic glycolysis and the pentose phosphate pathway (PPP) during epithelial-mesenchymal transition (EMT) is not well-understood. Here we show that Snail (SNAI1), a key transcriptional repressor of EMT, regulates glucose flux toward PPP, allowing cancer cel...
Profiling of miRNA expressions comparing standard fracture healing models with nonunion models in rats 12w, male, Sprague–Dawley rats were used in this study. Animals were randomized to receive either a surgical treatment that has been shown to produce a nonunion or to a standard stabilized closed f...
